BACKGROUND: The suppressive function of regulatory T (Treg) cells is compromised in
allergic individuals, and the augmentation of Treg cells has been demonstrated after …

Effects of allergen immunotherapy on follicular regulatory T... : Current Opinion in Allergy and
Clinical Immunology Effects of allergen immunotherapy on follicular regulatory T cells : Current …

Background Allergen‐specific immunotherapy (AIT) is the only available treatment for
allergic diseases that can induce specific immune tolerance to allergens. The key …

Subcutaneous specific immunotherapy (SCIT) has been shown to modify the
Dermatophagoides pteronissinus (DP) allergic response, characterized by generation of …

Background Specific immunotherapy with whole allergen extracts is associated with local
accumulation of IFN‐γ+ and CD25+ cells indicating recruitment of activated T‐helper type 1 …

Background The function of follicular regulatory T (T FR) cells, especially in regulating IgE
production in patients with allergic diseases, is poorly understood. Objective We sought to …

Background: Allergen-specific sublingual immunotherapy is a potential treatment for allergic
diseases. Its effective dose and underlying mechanism are still to be explored. Here, we …

The immunoglobulin E (IgE) high-affinity receptor FcεRI expressed on mast cells and
basophils plays a critical role in triggering allergic disease. The co-aggregation of the FcεRI …

A major pathway for the development of allergic disease is the production of IgE antibodies
specific for allergenic antigens. Once IgE is bound to mast cells and basophils via the high …

Background: Allergen-specific immunotherapy (SIT) is a highly effective treatment for allergic
diseases, but the underlying mechanisms are unclear. In this study, we investigated the …