[PDF][PDF] T follicular helper cells mediate local production of allergen-specific IgE and IgG4

M Akiyama, Y Kaneko, T Takeuchi - Journal of Allergy and Clinical …, 2022 - Elsevier
The prevalence of allergies such as allergic conjunctivitis, allergic rhinitis, rhinosinusitis,
bronchial asthma, and food allergies has been increasing in recent years, and allergic …

Mechanisms of allergen-specific immunotherapy

CA Akdis, M Akdis - Journal of Allergy and Clinical Immunology, 2011 - Elsevier
Allergen-specific immunotherapy has been used for 100 years as a desensitizing therapy for
allergic diseases and represents the potentially curative and specific method of treatment …

Suppression of Allergic Inflammation by Allergen‐DNA‐modified Dendritic Cells Depends on the Induction of Foxp3+ Regulatory T Cells

K Wu, Y Bi, K Sun, J Xia, Y Wang… - Scandinavian journal of …, 2008 - Wiley Online Library
Abstract CD4+ CD25+ Foxp3+ Regulatory T cells (Tregs) play important roles in regulating
allergic inflammation. To analyse if allergen‐DNA‐modified dendritic cells (DC) can …

FcεRI levels and frequencies of peripheral blood dendritic cell populations in allergic rhinitis

K Lundberg, L Greiff, CAK Borrebaeck, M Lindstedt - Human Immunology, 2010 - Elsevier
The dendritic cell (DC) lineage encompasses a diverse population of cells with unique
subtype-specific functions. In peripheral blood, four DC subsets have been identified based …

The levels of CD4+CD25+ regulatory T cells in paediatric patients with allergic rhinitis and bronchial asthma

JH Lee, HH Yu, LC Wang, YH Yang… - Clinical & …, 2007 - academic.oup.com
Our purpose was to determine whether numbers of CD4+ CD25+ T [T regulatory (Treg)] cells
and mRNA expression of functional molecules of Treg are related to airway allergy and …

Mechanisms of allergen-specific immunotherapy

M Akdis, CA Akdis - Journal of Allergy and Clinical Immunology, 2007 - Elsevier
Allergen-specific immunotherapy (SIT) has been used for almost a century as a
desensitizing therapy for allergic diseases and represents the only curative and specific …

[PDF][PDF] T-cell receptor peptides that inhibit the T-cell response to allergen induce transforming growth factor-β1 production

CM Hawrylowicz, ER Jarman, L Guida… - Journal of allergy and …, 1996 - academia.edu
METHODS Separation of peripheral blood mononuclear cells (PBMCs) from healthy adults
by Ficoll-Hypaque density, centrifugation and CD4+ and CD8+ T-cell depletion protocols …

Induction of bystander tolerance and immune deviation after Fel d 1 peptide immunotherapy

DM Moldaver, MS Bharhani, CD Rudulier… - Journal of Allergy and …, 2019 - Elsevier
Background Treatment of patients with cat allergy with peptides derived from Fel d 1 (the
major cat allergen) ameliorated symptoms of cat allergy in phase 2 clinical trials. Objective …

The effect of Fel d 1‐derived T‐cell peptides on upper and lower airway outcome measurements in cat‐allergic subjects

C Alexander, M Tarzi, M Larche, AB Kay - Allergy, 2005 - Wiley Online Library
Background: We previously showed that overlapping Fel d 1‐derived T‐cell peptides
inhibited surrogate markers of allergy (ie early and late‐phase skin reactions and T‐cell …

Allergen‐specific immunotherapy induces regulatory T cells in an atopic dermatitis mouse model

JU Shin, SH Kim, JY Noh, JH Kim, HR Kim, KY Jeong… - Allergy, 2018 - Wiley Online Library
Background Several studies have demonstrated that allergen‐specific immunotherapy (SIT)
can be an effective treatment for atopic dermatitis (AD). However, there is no relevant mouse …