[HTML][HTML] Procalcitonin-guided antibiotic therapy may shorten length of treatment and may improve survival—a systematic review and meta-analysis

M Papp, N Kiss, M Baka, D Trásy, L Zubek, P Fehérvári… - Critical Care, 2023 - Springer
Background Appropriate antibiotic (AB) therapy remains a challenge in the intensive care
unit (ICU). Procalcitonin (PCT)-guided AB stewardship could help optimize AB treatment and …

[HTML][HTML] Effect of procalcitonin-guided antibiotic treatment on clinical outcomes in intensive care unit patients with infection and sepsis patients: a patient-level meta …

Y Wirz, MA Meier, L Bouadma, CE Luyt, M Wolff… - Critical care, 2018 - Springer
Background The clinical utility of serum procalcitonin levels in guiding antibiotic treatment
decisions in patients with sepsis remains unclear. This patient-level meta-analysis based on …

[HTML][HTML] Procalcitonin-guided antibiotics in severe sepsis

P Simon, EB Milbrandt, LL Emlet - 2008 - Springer
Background The duration of antibiotic therapy in critically ill patients with sepsis can result in
antibiotic overuse, increasing the risk of developing bacterial resistance. Procalcitonin (PCT) …

[HTML][HTML] Cost-effectiveness of procalcitonin testing to guide antibiotic treatment duration in critically ill patients: results from a randomised controlled multicentre trial in …

MMA Kip, JA van Oers, A Shajiei, A Beishuizen… - Critical care, 2018 - Springer
Background Procalcitonin (PCT) testing can help in safely reducing antibiotic treatment
duration in intensive care patients with sepsis. However, the cost-effectiveness of such PCT …

Prognostic value of procalcitonin in respiratory tract infections across clinical settings

A Kutz, B Mueller, P Schuetz, IPD Study Group - Critical care, 2015 - Springer
Methods We analyzed data from 14 trials and 4,211 ARI patients to study associations of
admission PCT levels and setting specific treatment failure and mortality alone at 30 days …

[HTML][HTML] Procalcitonin-guided therapy in intensive care unit patients with severe sepsis and septic shock–a systematic review and meta-analysis

A Prkno, C Wacker, FM Brunkhorst, P Schlattmann - Critical care, 2013 - Springer
Introduction Procalcitonin (PCT) algorithms for antibiotic treatment decisions have been
studied in adult patients from primary care, emergency department, and intensive care unit …

[HTML][HTML] Procalcitonin kinetics within the first days of sepsis: relationship with the appropriateness of antibiotic therapy and the outcome

PE Charles, C Tinel, S Barbar, S Aho, S Prin, JM Doise… - Critical Care, 2009 - Springer
Introduction Management of the early stage of sepsis is a critical issue. As part of it, infection
control including appropriate antibiotic therapy administration should be prompt. However …

[HTML][HTML] Procalcitonin guidance for reduction of antibiotic use in patients hospitalized with severe acute exacerbations of asthma: a randomized controlled study with …

W Long, L Li, G Huang, X Zhang, Y Zhang, J Tang… - Critical care, 2014 - Springer
Introduction Patients with severe acute exacerbations of asthma often receive inappropriate
antibiotic treatment. We aimed to determine whether serum procalcitonin (PCT) levels can …

[HTML][HTML] Procalcitonin biomarker kinetics fails to predict treatment response in perioperative abdominal infection with septic shock

B Jung, N Molinari, M Nasri, Z Hajjej, G Chanques… - Critical care, 2013 - Springer
Introduction Procalcitonin (PCT) biomarker is suggested to tailor antibiotic therapy in the
medical intensive care unit (ICU) but studies in perioperative medicine are scarce. The aim …

[HTML][HTML] Ineffectiveness of procalcitonin-guided antibiotic therapy in severely critically ill patients: a meta-analysis

F Peng, W Chang, JF Xie, Q Sun, HB Qiu… - International Journal of …, 2019 - Elsevier
Background Optimizing antibiotic therapy has an important impact on the management of
critically ill patients. Procalcitonin (PCT) is considered to be of possible use in the guidance …