Leptin, the product of the obesity gene (ob) predominantly secreted from adipocytes, plays a
major role in the negative control of feeding and acts via a specific receptor (Ob‐R), six …

Leptin is a product of the obese (OB) gene secreted by adipocytes in proportion to fat mass.
It decreases food intake and increases energy expenditure by affecting the balance between …

As a growing number of people suffer from obesity, understanding the mechanisms by which
various hormones and neurotransmitters have influence on energy balance has been the …

A major advance in the understanding of the control of appetite, food intake, and energy
expenditure came with the discovery of leptin. Leptin concentrations correlate with adipose …

The identification of leptin allowed the discovery of a new endocrine system. This major
adipokine controlling energy homeostasis is also involved in the regulation of …

Leptin is a newly discovered hormone that acts as a feedback signal from the adipose
tissue. It plays a pivotal role in the modulation of neuronal and hormonal systems involved in …

The identification and sequencing of the ob gene and its product, leptin, in late 1994 opened
new insights in the study of the mechanisms controlling body weight and led to a surge of …

Focuses on the role of leptin, a hormone synthesized in fat cells, in weight regulation of
patients with anorexia nervosa. Correlation of serum levels of leptin with body mass index …

Leptin has received considerable attention as a newly recognized metabolic hormone and
for its potential for therapeutic use in the treatment of human obesity. Furthermore, defects in …