Leptin is a hormone with pleiotropic functions affecting several tissues. Because leptin has a
crucial role in the adaptation of an organism to semi-starvation, anorexia nervosa (AN) …

Leptin is a hormone secreted by adipocytes, stomach and placenta. Age, sex, puberty onset
and food intake are the most important physiological factors that determines leptin …

Leptin is a mainly adipocyte-secreted protein that was discovered 5 years ago. Most of the
research following this discovery focused on the role of leptin in body weight regulation …

The discovery of leptin was a major breakthrough in our understanding of the role of adipose
tissue as a storage and secretory organ. Leptin was initially thought to act mainly to prevent …

Leptin is an adipocyte-derived hormone that is essential for normal body weight regulation.
Its main physiological role may be to coordinate the metabolic, endocrine and behavioural …

Since its discovery, leptin (a 167‐amino acid product of the OB gene) has quickly moved to
the forefront as an important hormone for regulation of energy balance. It closes a feedback …

Purpose: To review recent advances in the pathophysiology and potential clinical
applications of leptin, an adipose tissue-derived hormone. Data Sources: A MEDLINE …

The discovery of leptin in 1994 revolutionized our knowledge of the role of adipose tissue in
nutrition. This hormone is synthesized in adipocytes, and the cell membrane of most cells …

Leptin was discovered in 1994 (20 years ago). In addition to having well-characterized
effects on the regulation of energy homeostasis, leptin clearly also plays a major role in …

Leptin is a 167-amino-acid protein released by white adipose tissue and encoded by the
obese gene. It has a role as a negative regulator of appetite control through sending a …