Self-assembling supramolecular dendrimers for biomedical applications: Lessons learned from poly (amidoamine) dendrimers

Z Lyu, L Ding, A Tintaru, L Peng - Accounts of Chemical Research, 2020 - ACS Publications
Conspectus Dendrimers, notable for their well-defined radial structures with numerous
terminal functionalities, hold great promise for biomedical applications such as drug …

Poly (amidoamine)(PAMAM) dendrimers: from biomimicry to drug delivery and biomedical applications

R Esfand, DA Tomalia - Drug discovery today, 2001 - Elsevier
Poly (amidoamine)(PAMAM) dendrimers are the first complete dendrimer family to be
synthesized, characterized and commercialized. Based on this extensive activity, they are …

Poly (amidoamine) dendrimers: Covalent and supramolecular synthesis

Z Lyu, L Ding, AYT Huang, CL Kao, L Peng - Materials Today Chemistry, 2019 - Elsevier
Dendrimers, a class of synthetic macromolecules which are notable for their well-defined
ramified structures and unique multivalent cooperativity, hold great promise for developing …

Dendrimers as multi-purpose nanodevices for oncology drug delivery and diagnostic imaging

DA Tomalia, LA Reyna, S Svenson - 2007 - portlandpress.com
Dendrimers are routinely synthesized as tuneable nanostructures that may be designed and
regulated as a function of their size, shape, surface chemistry and interior void space. They …

Bioinspired application of dendrimers: from bio-mimicry to biomedical applications

WD Jang, KMK Selim, CH Lee, IK Kang - Progress in Polymer Science, 2009 - Elsevier
Over the past few years, utilization of dendrimers in nano-biotechnology applications such
as bio-mimicry, diagnostics, and therapeutics has attracted a great deal of attention, far …

Dendrimers in supramolecular chemistry: from molecular recognition to self-assembly

F Zeng, SC Zimmerman - Chemical reviews, 1997 - ACS Publications
Dendrimers, also known as arborols, or cascade, cauliflower, or starburst polymers are
attracting increasing attention because of their unique structures and properties. 1r6 These …

Synthesis and functional evaluation of DNA-assembled polyamidoamine dendrimer clusters for cancer cell-specific targeting

Y Choi, T Thomas, A Kotlyar, MT Islam, JR Baker - Chemistry & biology, 2005 - cell.com
We sought to produce dendrimers conjugated to different biofunctional moieties (fluorescein
[FITC] and folic acid [FA]), and then link them together using complementary DNA …

Application of dendrimers in anticancer diagnostics and therapy

Z Bober, D Bartusik-Aebisher, D Aebisher - Molecules, 2022 - mdpi.com
The application of dendrimeric constructs in medical diagnostics and therapeutics is
increasing. Dendrimers have attracted attention due to their compact, spherical three …

Superstructured poly (amidoamine) dendrimer-based nanoconstructs as platforms for cancer nanomedicine: A concise review

C Song, M Shen, J Rodrigues, S Mignani… - Coordination Chemistry …, 2020 - Elsevier
Abstract Poly (amidoamine)(PAMAM) dendrimers, as a family of synthetic macromolecules
with highly branched interiors, abundant surface functional groups, and well-controlled …

Dendrimers: synthesis, applications, and properties

E Abbasi, SF Aval, A Akbarzadeh, M Milani… - Nanoscale research …, 2014 - Springer
Dendrimers are nano-sized, radially symmetric molecules with well-defined, homogeneous,
and monodisperse structure that has a typically symmetric core, an inner shell, and an outer …