Background: Alzheimer's Disease (AD) is one of the most common neurodegenerative
disorders, characterized by memory deficits and cognitive impairment. Acetylcholinesterase …

Due to multi-faceted pathology of AD; no drug can seize the progress of the disease,
whereas only the symptomatic treatment is available at the moment. Several drug classes to …

Complex diseases (eg, Alzheimer's disease) or infectious diseases are usually caused by
complicated and varied factors, including environmental and genetic factors. Multi-target …

Alzheimer's disease (AD) is a multifactorial syndrome resulting in profound misery and
poses a substantial burden on human health, economy, and society throughout the world …

Among the various drug discovery methods, a very promising modern approach consists in
designing multi-target-directed ligands (MTDLs). This methodology has been specifically …

We describe herein the therapeutic targets involved in Alzheimer's disease as well as the
available drugs and their synthetic routes. Bioactive compounds under development are …

Alzheimer's disease (AD) is a multifactorial syndrome with several target proteins
contributing to its etiology. To confront AD, an innovative strategy is to design single …

Alzheimer's disease (AD) belongs to the most intensively investigated and discussed
disorders in modern medicine and community worldwide. Only few clinical diagnoses evoke …

Background: Alzheimer's disease (AD) is a multifactorial neurodegenerative disease, and a
drug which targets a single protein would not provide a cure for this disease. Currently …

Alzheimer's disease (AD) is a progressive multifactorial neurodegenerative disorder.
Currently, no effective treatment is available and this is due to multiple factors involved in …