Transmissible strains of Pseudomonas aeruginosa in cystic fibrosis lung infections

JL Fothergill, MJ Walshaw… - European Respiratory …, 2012 - Eur Respiratory Soc
Pseudomonas aeruginosa chronic lung infections are the major cause of morbidity and
mortality associated with cystic fibrosis. For many years, the consensus was that cystic …

Genomic variation among contemporary Pseudomonas aeruginosa isolates from chronically infected cystic fibrosis patients

JCS Chung, J Becq, L Fraser… - Journal of …, 2012 - Am Soc Microbiol
The airways of individuals with cystic fibrosis (CF) often become chronically infected with
unique strains of the opportunistic pathogen Pseudomonas aeruginosa. Several lines of …

Infections with Pseudomonas aeruginosa in patients with cystic fibrosis.

B Tümmler, J Bosshammer, S Breitenstein… - Behring Institute …, 1997 - europepmc.org
The lung infection with Pseudomonas aeruginosa is regarded as one of the major causes of
health decline in patients with cystic fibrosis (CF). The CF host response to the persistent …

[HTML][HTML] Phenotypic diversity within a Pseudomonas aeruginosa population infecting an adult with cystic fibrosis

ST Clark, J Diaz Caballero, M Cheang, B Coburn… - Scientific reports, 2015 - nature.com
Chronic airway infections caused by Pseudomonas aeruginosa contribute to the
progression of pulmonary disease in individuals with cystic fibrosis (CF). In the setting of CF …

Evolutionary genomics of epidemic and nonepidemic strains of Pseudomonas aeruginosa

JR Dettman, N Rodrigue, SD Aaron… - Proceedings of the …, 2013 - National Acad Sciences
Pseudomonas aeruginosa is an opportunistic pathogen of humans and is a major cause of
morbidity and mortality in patients with cystic fibrosis (CF). Prolonged infection of the …

Differential adaptation of microbial pathogens to airways of patients with cystic fibrosis and chronic obstructive pulmonary disease

G Döring, IG Parameswaran… - FEMS microbiology …, 2011 - academic.oup.com
Cystic fibrosis (CF), the most common autosomal recessive disorder in Caucasians, and
chronic obstructive pulmonary disease (COPD), a disease of adults, are characterized by …

Pseudomonas aeruginosa Population Diversity and Turnover in Cystic Fibrosis Chronic Infections

E Mowat, S Paterson, JL Fothergill… - American journal of …, 2011 - atsjournals.org
Rationale: Pseudomonas aeruginosa isolates from chronic cystic fibrosis lung infections
display multiple phenotypes indicating extensive population diversity. Objectives: We aimed …

Divergent, Coexisting Pseudomonas aeruginosa Lineages in Chronic Cystic Fibrosis Lung Infections

D Williams, B Evans, S Haldenby… - American journal of …, 2015 - atsjournals.org
Rationale: Pseudomonas aeruginosa, the predominant cause of chronic airway infections of
patients with cystic fibrosis, exhibits extensive phenotypic diversity among isolates within …

Epidemiology, biology, and impact of clonal Pseudomonas aeruginosa infections in cystic fibrosis

MD Parkins, R Somayaji, VJ Waters - Clinical microbiology …, 2018 - Am Soc Microbiol
Chronic lower airway infection with Pseudomonas aeruginosa is a major contributor to
morbidity and mortality in individuals suffering from the genetic disease cystic fibrosis (CF) …

[HTML][HTML] Comparative genomics and biological characterization of sequential Pseudomonas aeruginosa isolates from persistent airways infection

I Bianconi, J Jeukens, L Freschi, B Alcalá-Franco… - BMC genomics, 2015 - Springer
Background Pseudomonas aeruginosa establishes life-long chronic airway infections in
cystic fibrosis (CF) patients. As the disease progresses, P. aeruginosa pathoadaptive …