This review summarizes the proceedings of a symposium presented at the “Alcoholism and
Stress: A Framework for Future Treatment Strategies” conference held in Volterra, Italy on …

Genetic mechanisms of alternative mRNA splicing have been shown in the brain for a
variety of neuropsychiatric traits, but not substance use disorders. Our study utilized RNA …

Background Genomewide association studies (GWAS) have begun to identify loci related to
alcohol consumption, but little is known about whether this genetic propensity overlaps with …

The abuse of alcohol, one of the most popular psychoactive substances, can cause several
pathological and psychological consequences, including alcohol use disorder (AUD). An …

Alcohol dependence (AD) is among the most common and costly public health problems
contributing to morbidity and mortality throughout the world. In this study, we investigate the …

Association genome scanning can identify markers for the allelic variants that contribute to
vulnerability to complex disorders, including alcohol dependence. To improve the power …

Age at onset of alcohol dependence (AO-AD) is a defining feature of multiple drinking
typologies. AO-AD is heritable and likely shares genetic liability with other aspects of alcohol …

Background Habitual alcohol use can be an indicator of alcohol dependence, which is
associated with a wide range of serious health problems. Methods We completed a genome …

Background: Alcohol dependence is a complex disease, and although linkage and
candidate gene studies have identified several genes associated with the risk for …

Background Despite the profound clinical significance and strong heritability of alcohol use
disorder (AUD), we do not yet have a comprehensive understanding of the naturally …