[HTML][HTML] Prospects for advancing tuberculosis control efforts through novel therapies
Background Development of new, effective, and affordable tuberculosis (TB) therapies has
been identified as a critical priority for global TB control. As new candidates emerge from the …
been identified as a critical priority for global TB control. As new candidates emerge from the …
[HTML][HTML] Confronting the scientific obstacles to global control of tuberculosis
DB Young, MD Perkins, K Duncan… - The Journal of clinical …, 2008 - Am Soc Clin Investig
Tuberculosis (TB) is a major threat to global health, recently exacerbated by the emergence
of highly drug-resistant forms of the disease-causing pathogen and synergy with HIV/AIDS …
of highly drug-resistant forms of the disease-causing pathogen and synergy with HIV/AIDS …
More tailored approaches to tuberculosis treatment and prevention
CM Bark, WH Boom, JJ Furin - Annual Review of Medicine, 2024 - annualreviews.org
Recent advances in the treatment of tuberculosis (TB) have led to improvements
unprecedented in our lifetime. Decades of research in developing new drugs, especially for …
unprecedented in our lifetime. Decades of research in developing new drugs, especially for …
[HTML][HTML] Priority-setting for novel drug regimens to treat tuberculosis: an epidemiologic model
Background Novel drug regimens are needed for tuberculosis (TB) treatment. New regimens
aim to improve on characteristics such as duration, efficacy, and safety profile, but no single …
aim to improve on characteristics such as duration, efficacy, and safety profile, but no single …
[HTML][HTML] Tuberculosis: Past, present and future of the treatment and drug discovery research
Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium
tuberculosis. Despite decades of research driving advancements in drug development and …
tuberculosis. Despite decades of research driving advancements in drug development and …
[HTML][HTML] Advances in diagnostics and drug discovery against resistant and latent tuberculosis infection
C Shleider Carnero Canales, J Marquez Cazorla… - Pharmaceutics, 2023 - mdpi.com
Latent tuberculosis infection (LTBI) represents a subclinical, asymptomatic mycobacterial
state affecting approximately 25% of the global population. The substantial prevalence of …
state affecting approximately 25% of the global population. The substantial prevalence of …
[HTML][HTML] Population-level impact of shorter-course regimens for tuberculosis: a model-based analysis
Despite current control efforts, global tuberculosis (TB) incidence is decreasing slowly. New
regimens that can shorten treatment hold promise for improving treatment completion and …
regimens that can shorten treatment hold promise for improving treatment completion and …
New initiative speeds tuberculosis drug development: novel drug regimens become possible in years, not decades
M Spigelman, R Woosley… - The international journal …, 2010 - ingentaconnect.com
NEW TOOLS to improve the treatment and control of tuberculosis (TB) are a critical
component of any comprehensive strategy to eradicate the global TB epidemic. In particular …
component of any comprehensive strategy to eradicate the global TB epidemic. In particular …
Recent advances in the treatment of tuberculosis
Background Tuberculosis (TB) is a global health challenge and one of the leading causes of
death worldwide. In the last decade, the TB treatment landscape has dramatically changed …
death worldwide. In the last decade, the TB treatment landscape has dramatically changed …
Tuberculosis 2015: burden, challenges and strategy for control and elimination
M Raviglione, G Sulis - Infectious disease reports, 2016 - mdpi.com
Tuberculosis (TB) is a leading cause of morbidity and mortality worldwide, accounting for
about 9.6 million new cases and 1.5 million deaths annually. The poorest and socially …
about 9.6 million new cases and 1.5 million deaths annually. The poorest and socially …