Graphene‐oxide‐based enzyme nanoarchitectonics for substrate channeling

M Mathesh, J Liu, CJ Barrow… - Chemistry–A European …, 2017 - Wiley Online Library
The controlled spatial organization or compartmentalization of multi‐enzyme cascade
reactions to transfer a substrate from one enzyme to another for substrate channeling on …

Biocatalytic cascades operating on macromolecular scaffolds and in confined environments

M Vázquez-González, C Wang, I Willner - Nature Catalysis, 2020 - nature.com
Biocatalytic cascades guide complex, efficient and selective intracellular transformations.
These unique features originate from the spatial organization of the biocatalysts in confined …

Conformational selection as the mechanism of guest binding in a flexible supramolecular host

CM Hong, DM Kaphan, RG Bergman… - Journal of the …, 2017 - ACS Publications
This study offers a detailed mechanistic investigation of host–guest encapsulation behavior
in a new enzyme–mimetic metal–ligand host and provides the first observation of a …

Recent trends in enzyme immobilization—concepts for expanding the biocatalysis toolbox

HJ Federsel, TS Moody, SJC Taylor - Molecules, 2021 - mdpi.com
Enzymes have been exploited by humans for thousands of years in brewing and baking, but
it is only recently that biocatalysis has become a mainstream technology for synthesis …

Tailoring enzyme microenvironment: State-of-the-art strategy to fulfill the quest for efficient bio-catalysis

M Bilal, J Cui, HMN Iqbal - International journal of biological …, 2019 - Elsevier
Enzymes as green industrial biocatalysts have become a powerful norm that offers several
advantages over traditional catalytic agents with regard to process efficiency, reusability …

Trends in the development of innovative nanobiocatalysts and their application in biocatalytic transformations

E Gkantzou, AV Chatzikonstantinou, R Fotiadou… - Biotechnology …, 2021 - Elsevier
The ever-growing demand for cost-effective and innocuous biocatalytic transformations has
prompted the rational design and development of robust biocatalytic tools. Enzyme …

Recent progress in multienzymes co-immobilization and multienzyme system applications

S Ren, C Li, X Jiao, S Jia, Y Jiang, M Bilal… - Chemical Engineering …, 2019 - Elsevier
Enzyme catalysis has been attracting increasing interest in the past twenty years.
Nevertheless, most reports concerning enzyme catalysis have been carried out using single …

Carrier‐free immobilization of multi‐enzyme complex facilitates in vitro synthetic enzymatic biosystem for biomanufacturing

M Liu, Y Song, YHPJ Zhang, C You - ChemSusChem, 2023 - Wiley Online Library
A method is developed for carrier‐free immobilization of multi‐enzyme complexes with more
than four enzymes by utilization of polypeptide interactions (SpyCatcher‐SpyTag and …

Enhanced Enzyme Activity through Scaffolding on Customizable Self‐Assembling Protein Filaments

S Lim, GA Jung, DJ Glover, DS Clark - Small, 2019 - Wiley Online Library
Precisely organized enzyme complexes are often found in nature to support complex
metabolic reactions in a highly efficient and specific manner. Scaffolding enzymes on …

Stabilization of multimeric enzymes via immobilization and post-immobilization techniques

R Fernández-Lafuente, V Rodrı́guez, C Mateo… - Journal of molecular …, 1999 - Elsevier
Controlled and directed immobilization plus post-immobilization techniques are proposed to
get full stabilization of the quaternary structure of most multimeric industrial enzymes. The …