The development of biological methods over the past decade has stimulated great interest in
the possibility to regenerate human tissues. Advances in stem cell research, gene therapy …

▪ Abstract Broadly defined, the concept of gene therapy involves the transfer of genetic
material into a cell, tissue, or whole organ, with the goal of curing a disease or at least …

Tissue engineering is a newly emerging biomedical form to create a local environment
which enables cells to promote the proliferation and differentiation for regeneration …

Gene therapy is one of the most attractive fields in medicine. The concept of gene delivery to
tissues for clinical applications has been discussed around half a century, but scientist's …

Gene therapy is a medical/surgical intervention currently being developed, in which genes
are introduced into cells in order to treat or cure a wide variety of human diseases. The field …

• Introduction• Methods of gene delivery‐Non‐viral techniques‐Naked DNA‐Cationic
liposomes‐Viral techniques‐Retrovirus‐Adenovirus‐Adeno‐associated virus‐Herpes …

Over the last decade, research in somatic gene therapy has focused on selected
approaches to deliver therapeutic genes to cells both ex vivo and in vivo. While most current …

Gene therapy aims at transferring a therapeutic gene into human somatic cells in order to
treat a disease. Originally addressed to hereditary genetic disorders, gene therapy has …

One factor critical to successful human gene therapy is development of efficient gene
delivery systems. Although numerous vector systems for gene transfer have been …

The use of nonviral plasmid-based gene medicines represents an attractive in vivo gene
transfer strategy that is simple and lacks many risks that are inherent to viral systems …