Human gene therapy can be defined as the delivery of genetic material into a patient's cells
with a therapeutic aim. The success or failure of gene therapy depends on the development …

The development over the past decade of methods for delivering genes to mammalian cells
has stimulated great interest in the possibility of treating human disease by gene-based …

Stem cell and gene therapy approaches have held out much hope for the development of
new tools to treat disease. Therapeutic approaches based on these methods have only …

Gene therapy is defined as the introduction of a therapeutic gene into a cell, whose
expression can lead to a cure of a disease or offer a transient advantage for tissue growth …

Gene therapy is used to correct genetic defects or to deliver new therapeutic functions to the
target cells. Viral vectors are employed mainly as a gene delivery system. A great variety of …

The present article is an overview of gene therapy with an emphasis on different approaches
and its implications in the clinic. Genetic interventions have been applied to the diagnosis of …

The last 10 years have seen substantial progress in the development and application of
nonviral vectors in gene therapy. Several novel nonviral methods have been developed that …

Methods As there are multiple options in selecting gene transfer vehicles among the non-
viral and viral vectors, there are also many options among the different transplantable cell …

Gene therapy is the treatment of diseases based on the transfer of genetic information.
Agents that carry or deliver DNA to target cells are called vectors (Latin vector: carrier …

Over the last three decades, interest in the field of gene therapy seems to have fluctuated
between hot and cold. Encouraging pre-clinical and clinical data has demonstrated the …