Tissue engineering is an interdisciplinary field that applies the principles of engineering and
life sciences toward the development of biological substitutes that restore, maintain or …

Development of an efficient method of gene introduction to target cells is the key issue in
treating genetic and acquired diseases by in vivo gene therapy. Although various nonviral …

Safe and effective gene delivery is a prerequisite for successful gene therapy. In the early
age of human gene therapy, setbacks due to problematic gene delivery vehicles plagued …

Gene therapy is the delivery of new genetic material into a patient's somatic cells for the
treatment of disease and is made possible through the development of viral and non-viral …

This review highlights the advances at the interface between tissue engineering and gene
therapy. There are a large number of reports on gene therapy in tissue engineering, and …

Gene therapy is a newly emerging field of biomedical research aimed at introducing
therapeutically important genes into somatic cells of patients; a new and revolutionary era in …

Gene therapies are currently one of the most investigated therapeutic modalities in both the
preclinical and clinical settings and have shown promise in treating a diverse spectrum of …

To the Editor: Gene therapy has promised much and delivered little for patients over many
years, but a range of clinical projects are now showing clear signs of efficacy, giving …

Background Organ fragments can be cultured for weeks in vitro if they are prepared of
microscopic thickness and if the basic organ structure is preserved. Such organ fragments …

Gene therapy has been proposed for a wide variety of human conditions including
monogenic disorders, such as the haemoglobinopathies and immunodeficiency syndromes …