The goal of this study was to clarify the synergistic antibacterial activity of the combination of
tigecycline (TGC) and rifampicin (RIF). Additionally, the study sought to investigate the …

Abstract Objectives Carbapenem-resistant Klebsiella pneumoniae (CR-KP) infections
represent severe threats to public health worldwide. The aim of this study was to assess …

Tigecycline is a last-resort antibiotic for infections caused by carbapenem-resistant
Klebsiella pneumoniae (CRKP). This study aimed to broaden our understanding of the …

The increasing incidence of tigecycline resistance undoubtedly constitutes a serious threat
to global public health. The combination therapies had become the indispensable strategy …

Objectives Tigecycline is an antibacterial agent restricted for use against carbapenem-
resistant Klebsiella pneumoniae (CRKP). This study aimed to identify the tigecycline …

Emergence of extensively drug-resistant isolates of Klebsiella pneumoniae has prompted
increased reliance on the last-resort antibiotics such as tigecycline (TGC) for treating …

Tigecycline has been used as one of the therapeutic choices for the treatment of infections
caused by multidrug-resistant Klebsiella pneumoniae. However, the emergence of …

Co-administration of antibiotics with synergistic effects is one method to combat carbapenem-
resistant organisms. Although the synergistic effects of tigecycline combined with …

By far, only tigecycline, colistin, and some aminoglycosides still show favorable in vitro
activities against carbapenem-resistant Enterobacteriaceae. However, rapid emergence of …

Objectives Tigecycline is a treatment option for infections caused by carbapenem-resistant
Klebsiella pneumoniae (CRKP). Emerging tigecycline resistance in CRKP represents a …