[HTML][HTML] Doxepin exacerbates renal damage, glucose intolerance, nonalcoholic fatty liver disease, and urinary chromium loss in obese mice
GR Chang, PH Hou, WC Yang, CM Wang, PS Fan… - Pharmaceuticals, 2021 - mdpi.com
Doxepin is commonly prescribed for depression and anxiety treatment. Doxepin-related
disruptions to metabolism and renal/hepatic adverse effects remain unclear; thus, the …
disruptions to metabolism and renal/hepatic adverse effects remain unclear; thus, the …
[HTML][HTML] Clozapine worsens glucose intolerance, nonalcoholic fatty liver disease, kidney damage, and retinal injury and increases renal reactive oxygen species …
Clozapine is widely employed in the treatment of schizophrenia. Compared with that of
atypical first-generation antipsychotics, atypical second-generation antipsychotics such as …
atypical first-generation antipsychotics, atypical second-generation antipsychotics such as …
[HTML][HTML] Pentoxifylline mitigates renal glycoxidative stress in obese mice by inhibiting AGE/RAGE signaling and increasing glyoxalase levels
MD Inacio, MC Costa, TFO Lima, ID Figueiredo… - Life Sciences, 2020 - Elsevier
Aim The pharmacological properties of pentoxifylline have been re-evaluated, particularly in
chronic kidney disease in diabetes, favored by its anti-inflammatory action. Definitive …
chronic kidney disease in diabetes, favored by its anti-inflammatory action. Definitive …
Gamma Oryzanol Treats Obesity‐Induced Kidney Injuries by Modulating the Adiponectin Receptor 2/PPAR‐α Axis
FV Francisqueti, AJT Ferron… - Oxidative medicine …, 2018 - Wiley Online Library
The kidney is an important organ in the maintenance of body homeostasis. Dietary
compounds, reactive metabolites, obesity, and metabolic syndrome (MetS) can affect renal …
compounds, reactive metabolites, obesity, and metabolic syndrome (MetS) can affect renal …
[HTML][HTML] Osthol ameliorates kidney damage and metabolic syndrome induced by a high-fat/high-sugar diet
FE García-Arroyo, G Gonzaga-Sánchez… - International Journal of …, 2021 - mdpi.com
Excessive intake of fructose results in metabolic syndrome (MS) and kidney damage, partly
mediated by its metabolism by fructokinase-C or ketohexokinase-C (KHK-C). Osthol has …
mediated by its metabolism by fructokinase-C or ketohexokinase-C (KHK-C). Osthol has …
Diacerein alleviates kidney injury through attenuating inflammation and oxidative stress in obese insulin-resistant rats
N Chueakula, K Jaikumkao, P Arjinajarn… - Free Radical Biology …, 2018 - Elsevier
A link between inflammation with obesity and metabolic syndrome has been found in
patients with chronic kidney disease (CKD). Diacerein is an anthraquinone used to treat …
patients with chronic kidney disease (CKD). Diacerein is an anthraquinone used to treat …
[HTML][HTML] Diosmin and crocin alleviate nephropathy in metabolic syndrome rat model: Effect on oxidative stress and low grade inflammation
R El-Fawal, HM El Fayoumi, MF Mahmoud - Biomedicine & …, 2018 - Elsevier
Nephropathy is a serious complication of metabolic syndrome (MS), a global epidemic
disorder. This study was undertaken to investigate the actions of diosmin and crocin, two …
disorder. This study was undertaken to investigate the actions of diosmin and crocin, two …
Emodin Attenuated the Kidney Damage of High‐Fat‐Diet Mice via the Upregulation of Glucagon‐Like Peptide‐1 Receptor
J Liu, Y Sun, H Zheng, J Wang, L Liu… - BioMed Research …, 2021 - Wiley Online Library
Objective. Secretion of glucagon‐like peptide 1 (GLP‐1) and its effect on target organs were
impaired in individuals with obesity. However, its mechanism needs to be further studied …
impaired in individuals with obesity. However, its mechanism needs to be further studied …
[HTML][HTML] Xanthine oxidase inhibitor febuxostat exerts an anti-inflammatory action and protects against diabetic nephropathy development in KK-Ay obese diabetic mice
Y Mizuno, T Yamamotoya, Y Nakatsu, K Ueda… - International Journal of …, 2019 - mdpi.com
Hyperuricemia has been recognized as a risk factor for insulin resistance as well as one of
the factors leading to diabetic kidney disease (DKD). Since DKD is the most common cause …
the factors leading to diabetic kidney disease (DKD). Since DKD is the most common cause …
Zoledronic acid-induced mitochondrial impairment, inflammation, and oxidative stress in the rat kidney
H Rezaei, A Rouhani, J Yüzügülen… - Trends in …, 2023 - tips.sums.ac.ir
Zoledronic acid (ZLD) is a bisphosphonate drug widely administered against pathological
conditions such as hypercalcemia of malignancy, osteoporosis, bone metastases from solid …
conditions such as hypercalcemia of malignancy, osteoporosis, bone metastases from solid …