From genetics to epigenetics to unravel the etiology of adolescent idiopathic scoliosis
G Pérez-Machado, E Berenguer-Pascual… - Bone, 2020 - Elsevier
Scoliosis is defined as the three-dimensional (3D) structural deformity of the spine with a
radiological lateral Cobb angle (a measure of spinal curvature) of≥ 10° that can be caused …
radiological lateral Cobb angle (a measure of spinal curvature) of≥ 10° that can be caused …
Idiopathic scoliosis: etiological concepts and hypotheses
R Dayer, T Haumont, W Belaieff… - Journal of children's …, 2013 - journals.sagepub.com
Scoliosis is diagnosed as idiopathic in 70% of structural deformities affecting the spine in
children and adolescents, probably reflecting our current misunderstanding of this disease …
children and adolescents, probably reflecting our current misunderstanding of this disease …
Adolescent idiopathic scoliosis
Adolescent idiopathic scoliosis (AIS) is the most common form of structural spinal deformities
that have a radiological lateral Cobb angle—a measure of spinal curvature—of≥ 10. AIS …
that have a radiological lateral Cobb angle—a measure of spinal curvature—of≥ 10. AIS …
Adolescent idiopathic scoliosis: a review of aetiological theories of a multifactorial disease
S Marya, AD Tambe, PA Millner… - The Bone & Joint …, 2022 - boneandjoint.org.uk
Adolescent idiopathic scoliosis (AIS), defined by an age at presentation of 11 to 18 years,
has a prevalence of 0.47% and accounts for approximately 90% of all cases of idiopathic …
has a prevalence of 0.47% and accounts for approximately 90% of all cases of idiopathic …
Epigenetic and genetic factors related to curve progression in adolescent idiopathic scoliosis: a systematic scoping review of the current literature
Adolescent idiopathic scoliosis (AIS) is a progressive deformity of the spine. Scoliotic curves
progress until skeletal maturity leading, in rare cases, to a severe deformity. While the Cobb …
progress until skeletal maturity leading, in rare cases, to a severe deformity. While the Cobb …
Exploring the association between specific genes and the onset of idiopathic scoliosis: a systematic review
S De Salvatore, L Ruzzini, UG Longo, M Marino… - BMC Medical …, 2022 - Springer
Abstract Background Idiopathic Scoliosis (IS) is the most common spinal deformity in
adolescents, accounting for 80% of all spinal deformities. However, the etiology remains …
adolescents, accounting for 80% of all spinal deformities. However, the etiology remains …
Whither the etiopathogenesis (and scoliogeny) of adolescent idiopathic scoliosis? Incorporating presentations on scoliogeny at the 2012 IRSSD and SRS meetings
RG Burwell, PH Dangerfield, A Moulton, TB Grivas… - Scoliosis, 2013 - Springer
This paper aims to integrate into current understanding of AIS causation, etiopathogenetic
information presented at two Meetings during 2012 namely, the International Research …
information presented at two Meetings during 2012 namely, the International Research …
Understanding genetic factors in idiopathic scoliosis, a complex disease of childhood
CA Wise, X Gao, S Shoemaker, D Gordon… - Current …, 2008 - ingentaconnect.com
Idiopathic scoliosis (AIS) is the most common pediatric spinal deformity, affecting∼ 3% of
children worldwide. AIS significantly impacts national health in the US alone, creating …
children worldwide. AIS significantly impacts national health in the US alone, creating …
Adolescent idiopathic scoliosis: evidence for intrinsic factors driving aetiology and progression
MMP Newton Ede, SW Jones - International orthopaedics, 2016 - Springer
Adolescent idiopathic scoliosis (AIS) is now considered to be a multifactorial heterogeneous
disease, with recent genomic studies supporting the role of intrinsic factors in contributing to …
disease, with recent genomic studies supporting the role of intrinsic factors in contributing to …
Recent advances in the aetiology of adolescent idiopathic scoliosis
The aetiology of adolescent idiopathic scoliosis (AIS) is still unknown despite many years of
research effort. Theories on AIS's aetiology have included mechanical, hormonal, metabolic …
research effort. Theories on AIS's aetiology have included mechanical, hormonal, metabolic …