Objective This investigation aimed at examining whether circulating inflammatory
biomarkers C-reactive protein (CRP), interleukin-6 (IL6), and alpha 1-antichymotrypsin …

Objective: The relation between inflammation and brain MRI findings in the elderly remains
poorly known. We investigated the association of circulating interleukin-6 (IL-6) and C …

Background and Purpose—To clarify the role of inflammation in the pathogenesis of small
vessel disease of the brain, we investigated the association between common variation in …

Background and purpose Although inflammation has been proposed to be a candidate risk
factor for cerebral small vessel disease (CSVD), previous findings remain largely …

Background and Purpose—Inflammation is involved in the pathogenesis of large artery
atherosclerosis, ischemic stroke, and Alzheimer dementia. However, the role of inflammation …

Objective: We investigated the association between circulating biomarkers of inflammation
and MRI markers of small vessel disease. Methods: We performed a cross-sectional study …

Inflammation is increasingly implicated as a risk factor for dementia, stroke, and small vessel
disease (SVD). However, the underlying mechanisms and causative pathways remain …

BACKGROUND: Proinflammatory state has been implicated as a pathogenetic mechanism
in the progression of intracranial large artery atherosclerosis (ILA). High levels of …

Background and Purpose—It is currently unclear whether midlife systemic inflammation
promotes the development of white matter (WM) abnormalities and small vessel disease in …

Background: The cause of lacunar ischemic stroke, a clinical feature of cerebral small vessel
disease (SVD), is largely unknown. Inflammation and endothelial dysfunction have been …