Melanoma (MEL) is a less common type of skin cancer, but it is more aggressive with a high
mortality rate. The World Cancer Research Fund International (GLOBOCAN 2012) estimates …

Melanoma is one of the most severe cancerous diseases. The cells employ multiple
signaling pathways, such as ERK, HGF/c-MET, WNT, and COX-2 to cause the cell …

Cutaneous melanoma (CM) is a multifactorial disease whose treatment still presents
challenges: the rapid progression to advanced CM, which leads to frequent recurrences …

Melanoma, the most aggressive form of cutaneous malignancy arising from melanocytes, is
frequently characterized by metastasis. Despite considerable progress in melanoma …

Melanoma is the most aggressive form of skin cancer and its annual incidence rates are
increasing globally. Though chemotherapy, radiotherapy, immunotherapy and targeted …

Melanoma is one of the most aggressive skin cancers, notorious for its high multidrug
resistance and low survival rate. Conventional therapies (eg, dacarbazine, interferon-alpha …

Melanoma, as a tumor cell derived from melanocyte transformation, has the characteristics
of malignant proliferation, high metastasis, rapid recurrence, and a low survival rate …

Melanoma is a most aggressive skin cancer with limited therapeutic options and its
incidence is increasing rapidly in recent years. The discovery and application of new …

Melanoma is an aggressive form of skin cancer with a high prevalence in the population. An
early diagnosis is crucial to cure this disease. Still, when this is not possible, combining …

Cutaneous melanoma is one of the most aggressive solid tumors, with a low survival for the
metastatic stage. Currently, clinical melanoma treatments include surgery, chemotherapy …