Role of lncRNAs in stem cell maintenance and differentiation

M Aich, D Chakraborty - Current topics in developmental biology, 2020 - Elsevier
Embryonic Stem cells are widely studied to elucidate the disease and developmental
processes because of their capability to differentiate into cells of any lineage, Pervasive …

Long noncoding RNAs in human stemness and differentiation

FM Azad, IL Polignano, V Proserpio, S Oliviero - Trends in Cell Biology, 2021 - cell.com
There is increasing evidence that long noncoding RNAs (lncRNAs) are among the main
regulatory factors of stem cell maintenance and differentiation. They act through various …

LncRNA functions as a new emerging epigenetic factor in determining the fate of stem cells

J Chen, Y Wang, C Wang, JF Hu, W Li - Frontiers in genetics, 2020 - frontiersin.org
Pluripotent stem cells have broad applications in regenerative medicine and offer ideal
models for understanding the biological process of embryonic development and specific …

Cis-and trans-acting lncRNAs in pluripotency and reprogramming

P Yan, S Luo, JY Lu, X Shen - Current opinion in genetics & development, 2017 - Elsevier
Highlights•Cis-and trans-acting lncRNAs are involved in stem cell pluripotency and
reprogramming.•lncRNA-mediated cis regulation of nearby transcription is a prevalent …

Long non-coding RNA in stem cell pluripotency and lineage commitment: functions and evolutionary conservation

A Fico, A Fiorenzano, E Pascale, EJ Patriarca… - Cellular and molecular …, 2019 - Springer
LncRNAs have recently emerged as new and fundamental transcriptional and post-
transcriptional regulators acting at multiple levels of gene expression. Indeed, lncRNAs …

Large noncoding RNAs are promising regulators in embryonic stem cells

YP Li, Y Wang - Journal of Genetics and Genomics, 2015 - Elsevier
Embryonic stem cells (ESCs) hold great promises for treating and studying numerous
devastating diseases. The molecular basis of their potential is not completely understood …

Functions of lncRNA in development and diseases

EL Mathieu, M Belhocine, LT Dao, D Puthier… - … Sciences: M/S, 2014 - europepmc.org
The transcription of essentially the entire eukaryotic genome generates a myriad of non-
coding RNA species that show complex overlapping patterns of expression and regulation …

Human long noncoding RNA regulation of stem cell potency and differentiation

S Lee, HH Seo, CY Lee, J Lee, S Shin… - Stem Cells …, 2017 - Wiley Online Library
Because of their capability of differentiation into lineage‐specific cells, stem cells are an
attractive therapeutic modality in regenerative medicine. To develop an effective stem cell …

LncRNAs and their RBPs: How to influence the fate of stem cells?

C Zhao, W Xie, H Zhu, M Zhao, W Liu, Z Wu… - Stem Cell Research & …, 2022 - Springer
Stem cells are distinctive cells that have self-renewal potential and unique ability to
differentiate into multiple functional cells. Stem cell is a frontier field of life science research …

LncRNAs in stem cells

S Hu, G Shan - Stem cells international, 2016 - Wiley Online Library
Noncoding RNAs are critical regulatory factors in essentially all forms of life. Stem cells
occupy a special position in cell biology and Biomedicine, and emerging results show that …