[HTML][HTML] How to Improve Prognostication in Acute Myeloid Leukemia with CBFB-MYH11 Fusion Transcript: Focus on the Role of Molecular Measurable Residual …

A Talami, F Bettelli, V Pioli, D Giusti, A Gilioli… - Biomedicines, 2021 - mdpi.com
Acute myeloid leukemia (AML) carrying inv (16)/t (16; 16), resulting in fusion transcript CBFB-
MYH11, belongs to the favorable-risk category. However, even if most patients obtain …

Prognostic Impact of Minimal Residual Disease inCBFB-MYH11–Positive Acute Myeloid Leukemia

A Corbacioglu, C Scholl, RF Schlenk… - Journal of Clinical …, 2010 - ascopubs.org
Purpose To evaluate the prognostic impact of minimal residual disease (MRD) in patients
with acute myeloid leukemia (AML) expressing the CBFB-MYH11 fusion transcript. Patients …

Prognostic value of minimal residual disease by real-time quantitative PCR in acute myeloid leukemia with CBFB-MYH11 rearrangement: the French experience

R Guieze, A Renneville, JM Cayuela, RB Abdelali… - Leukemia, 2010 - nature.com
Acute myeloid leukemia (AML) with inversion of chromosome 16 inv (16)(p13q22) or
balanced translocation t (16; 16)(p13; q22), which results in the fusion of CBFB to MYH11, is …

Assessment of minimal residual disease (MRD) in CBFbeta/MYH11-positive acute myeloid leukemias by qualitative and quantitative RT-PCR amplification of fusion …

A Guerrasio, C Pilatrino, D De Micheli, D Cilloni… - Leukemia, 2002 - nature.com
Abstract The inv (16)(p13q22) chromosomal rearrangement associated with FAB M4Eo
acute myeloid leukemia (AML) subtype is characterized by the presence of the …

Quantification of CBFB-MYH11 fusion gene levels in paired peripheral blood and bone marrow samples by real-time PCR

N Boeckx, J De Roover, VHJ Van Der Velden… - Leukemia, 2005 - nature.com
Inv (16)(p13q22) and the related translocation t (16; 16)(p13; q22) generate a CBFB-MYH11
fusion gene transcript and are commonly found in acute myeloid leukemia (AML) M4Eo. 1 …

Relevance of presenting white blood cell count and kinetics of molecular remission in the prognosis of acute myeloid leukemia with CBFbeta/MYH11 rearrangement

G Martín, E Barragán, P Bolufer, C Chillón… - …, 2000 - haematologica.org
BACKGROUND AND OBJECTIVES: The detection of CBFbeta/MYH11 transcripts by RT-
PCR has became a valuable and widely used technique in the accurate cytogenetic and …

Quantification of CBFβ/MYH11 fusion transcript by real time RT-PCR in patients with INV (16) acute myeloid leukemia

G Marcucci, MA Caligiuri, H Döhner, KJ Archer… - Leukemia, 2001 - nature.com
Amplification of the CBFβ/MYH11 fusion transcript by a qualitative reverse transcription-
polymerase chain reaction (RT-PCR) has been used to detect minimal residual disease …

Rare CBFB-MYH11 fusion transcripts in AML with inv (16)/t (16; 16) are associated with therapy-related AML M4eo, atypical cytomorphology, atypical …

S Schnittger, U Bacher, C Haferlach, W Kern… - Leukemia, 2007 - nature.com
The spectrum of CBFB-MYH11 fusion transcripts in acute myeloid leukemia (AML) M4eo
with inv (16)/t (16; 16) is heterogeneous. Approximately 85% show type A CBFB-MYH11 …

Molecular monitoring to identify a threshold of CBFbeta/MYH11 transcript below which continuous complete remission of acute myeloid leukemia inv16 is likely

G Martinelli, M Rondoni, S Buonamici… - …, 2004 - haematologica.org
Many patients with the inv (16) positive acute myeloid leukemia (AML) achieve complete
remission (CR). Using real-time reverse transcriptase polymerase chain reaction (RT-PCR) …

New score predicting for prognosis in PML-RARA+, AML1-ETO+, or CBFBMYH11+ acute myeloid leukemia based on quantification of fusion transcripts

S Schnittger, M Weisser, C Schoch, W Hiddemann… - Blood, 2003 - ashpublications.org
To evaluate the prognostic significance of quantitative PML-RARA, AML1-ETO, and CBFB-
MYH11 fusion transcript expression, real-time polymerase chain reaction was used to …