Autism Spectrum Disorder (ASD) is a behaviorally defined neurodevelopmental disorder
characterized by decreased reciprocal social interaction, abnormal communication, and …

Background: Human genetic studies have indicated that mutations in calcium/calmodulin-
dependent serine protein kinase (CASK) result in X-linked mental retardation and autism …

Neuropsychiatric disorders in which reduced social interest is a common symptom, such as
autism, depression, and anxiety, are frequently associated with genetic mutations affecting γ …

The genetically inbred BTBR T+ Itpr3tf/J (BTBR) mouse is a proposed model of autism
spectrum disorders (ASDs). Similar to several syndromic forms of ASDs, mTOR activity may …

Background: The CTNND2 gene which encodes a δ-catenin protein (CTNND2) is
associated with multiple severe neurological disorders. However, the specific role of …

Dravet syndrome (DS) is a catastrophic developmental and epileptic encephalopathy
characterized by severe, pharmaco-resistant seizures and a high risk of Sudden …

Gestational diabetes mellitus (GDM) was associated with greater autism risk in
epidemiological studies. Disrupted leptin signaling may contribute to their coincidence, as it …

Recently, deleterious variants in the BR serine/threonine kinase 2 (BRSK2) gene have been
reported in patients with autism spectrum disorder (ASD), suggesting that BRSK2 is a new …

Autism spectrum disorders (ASD) are a heterogeneous group of neurodevelopmental
disorders that affect communication and behavior. According to the centers for disease …

Brain-derived neurotrophic factor (Bdnf) has been implicated in several neurological
disorders including Rett syndrome (RTT), an X-linked neurodevelopmental disorder caused …