Dendrimer-based contrast agents for molecular imaging

M Longmire, PL Choyke… - Current topics in …, 2008 - ingentaconnect.com
The extensive adaptability of dendrimer-based contrast agents is ideal for the molecular
imaging of organs and other target-specific locations. The ability of literally atom-by-atom …

Applications of dendrimers in bio-organic chemistry

Y Kim, SC Zimmerman - Current opinion in chemical biology, 1998 - Elsevier
Dendrimers represent a new class of highly branched polymers whose interior cavities and
multiple peripheral groups facilitate potential applications in biomedicine and bio-organic …

PAMAM dendrimer based macromolecules as improved contrast agents

VJ Venditto, CAS Regino… - Molecular …, 2005 - ACS Publications
Dendrimers are an attractive platform for macromolecular imaging due to the presence of
multiple terminal groups on the exterior of the molecule. Through application of appropriate …

Dendrimer-based molecular imaging contrast agents

Z Qiao, X Shi - Progress in polymer science, 2015 - Elsevier
This review reports recent advances on the use of dendrimer nanotechnology to build up
various contrast agents for different single-mode or dual-mode molecular imaging …

Dendrimers in diagnostics

W Krause, N Hackmann-Schlichter, FK Maier… - Dendrimers II …, 2000 - Springer
Dendrimers are currently under investigation as potential polymeric carriers of contrast
agents for magnetic resonance imaging (MRI), scintigraphy and X-ray techniques, ie …

Dendrimer-based drug and imaging conjugates: design considerations for nanomedical applications

AR Menjoge, RM Kannan, DA Tomalia - Drug discovery today, 2010 - Elsevier
Dendrimers are members of a versatile, fourth new class of polymer architecture (ie dendritic
polymers after traditional linear, crosslinked and branched types)[1]. Typically, dendrimers …

Dendrimers as multi-purpose nanodevices for oncology drug delivery and diagnostic imaging

DA Tomalia, LA Reyna, S Svenson - 2007 - portlandpress.com
Dendrimers are routinely synthesized as tuneable nanostructures that may be designed and
regulated as a function of their size, shape, surface chemistry and interior void space. They …

Biomedical applications of dendrimers: a tutorial

MA Mintzer, MW Grinstaff - Chemical Society Reviews, 2011 - pubs.rsc.org
Since their development in the mid-80s, dendrimers have become prominent synthetic
macromolecules in the field of biomedical science. This tutorial review begins by discussing …

Toward improved syntheses of dendrimer-based magnetic resonance imaging contrast agents: new bifunctional diethylenetriaminepentaacetic acid ligands and …

H Xu, CAS Regino, M Bernardo… - Journal of medicinal …, 2007 - ACS Publications
Two different fourth-generation (G4) polyaminonamido dendrimer-based magnetic
resonsance (MR) agents were prepared by a new synthetic approach wherein tert-butyl …

Dendrimers as high relaxivity MR contrast agents

MR Longmire, M Ogawa, PL Choyke… - Wiley Interdisciplinary …, 2014 - Wiley Online Library
Dendrimers are versatile macromolecules with tremendous potential as magnetic resonance
imaging (MRI) contrast agents. Dendrimer‐based agents provide distinct advantages over …