The association between genetic variant of MDR1 gene and breast cancer risk factors in Chinese women

L Gao, Y Yang, S Song, H Hong, X Zhao, D Li - International …, 2013 - Elsevier
Previous studies indicated that the human multidrug resistance 1 gene (MDR1) is an
important candidate gene influencing the susceptibility to breast cancer. The purpose of this …

Association analysis between MDR1 genetic variant and breast cancer risk factors in Chinese Han population

Y Hu, J Wang, H Tao, H Wang, X Zhang, Y Cheng… - Medical Oncology, 2013 - Springer
The multidrug resistance 1 gene (MDR1) is an important candidate gene for influencing
breast cancer susceptibility. This study aimed to evaluate the association between MDR1 …

Investigation on MDR1 gene polymorphisms and its relationship with breast cancer risk factors in Chinese women

Y Fang, Q Zhao, G Ma, Y Han, N Lou - Medical Oncology, 2013 - Springer
The human multidrug resistance 1 gene (MDR1) is an important candidate gene influencing
the susceptibility to various diseases, including breast cancer. The object of this study was to …

The influence of genetic polymorphisms in MDR1 gene on breast cancer risk factors in Chinese

Y Jia, W Tian, S Sun, P Han, W Xue, M Li, Y Liu… - Medical Oncology, 2013 - Springer
Breast cancer (BC) is the most common cancer among women in the world. The human
multidrug resistance 1 gene (MDR1) is potentially an important gene influencing the …

A polymorphism C3435T of the MDR-1 gene associated with smoking or high body mass index increases the risk of sporadic breast cancer in women

P Zubor, Z Lasabova, J Hatok… - Oncology …, 2007 - spandidos-publications.com
The human multidrug resistance gene 1 (MDR-1) encodes a plasma membrane P-
glycoprotein (P-gp) that functions as the transmembrane efflux pump for various structurally …

Association between the MDR1 rs1045642 polymorphism and breast cancer risk: An updated meta‑analysis

L Gong, G Hu, L Xu, Y Chen… - Oncology …, 2024 - spandidos-publications.com
Abstract Multidrug resistance 1 (MDR1) is a transmembrane transporter on the cell
membrane. As an ATP‑dependent efflux pump, MDR1 is mainly responsible for the …

Association of C3435T Single-Nucleotide Polymorphism of MDR1 Gene with Breast Cancer in an Iranian Population

F Tatari, R Salek, F Mosaffa, A Khedri… - DNA and cell …, 2009 - liebertpub.com
The human multidrug resistance gene 1 (MDR1) encodes a plasma membrane, P-
glycoprotein (Pgp), which functions as the transmembrane efflux pump for various …

Association of multiple drug resistance-1 gene polymorphism with multiple drug resistance in breast cancer patients from an ethnic Saudi Arabian population

AA Alsaif, TN Hasan, G Shafi, NA Syed, MA Alsaif… - Cancer …, 2013 - Elsevier
Chemotherapy has been used widely to treat cancer, both as a systemic therapy and as a
local treatment. Unfortunately, many types of cancer are still refractory to chemotherapy. The …

[HTML][HTML] C3435T polymorphism in the MDR1 gene and breast cancer risk in northeastern Mexico

G Jaramillo-Rangel, M Ortega-Martínez… - … Journal of Clinical …, 2018 - ncbi.nlm.nih.gov
The multidrug resistance gene 1 (MDR1) encodes a membrane-bound phosphoglycoprotein
(P-gp). It functions as a transmembrane efflux pump for various structurally unrelated …

Clinical significance of expression of multidrug resistance gene in breast cancer tissue

X Liu, S Song, C Shi - Zhonghua yi xue za zhi, 1997 - europepmc.org
Objectives To investigate the role of expression of multidrug resistance gene (mdr-1 gene) in
chemotherapeutic resistance of breast cancer and to determine if expression of mdr-1 gene …