[PDF][PDF] Cardiac Endothelial Cells: Potential Therapeutic Targets in Heart Disease
KA Hemanthakumar - 2021 - helda.helsinki.fi
Cardiovascular diseases (CVD) rank as a number one cause for mortality and accounts for
one third of the deaths in several OECD countries (OECD, 2015). According to WHO, CVD …
one third of the deaths in several OECD countries (OECD, 2015). According to WHO, CVD …
[HTML][HTML] Cardiac endothelial cells: potential therapeutic targets in heart disease
K Amudhala Hemanthakumar - 2021 - helda.helsinki.fi
Cardiovascular diseases (CVD) rank as a number one cause for mortality and accounts for
one third of the deaths in several OECD countries (OECD, 2015). According to WHO, CVD …
one third of the deaths in several OECD countries (OECD, 2015). According to WHO, CVD …
Unconventional Roles of Endothelial Cells
L Iovino, G Krenning, B Hadland - Frontiers in Cell and Developmental … - frontiersin.org
For years, the only role attributed to the ECs was to trigger platelet aggregation and activate
coagulation factors (8, 9). However, it was later discovered that they also play a crucial role …
coagulation factors (8, 9). However, it was later discovered that they also play a crucial role …
Concerns and hopes for stem cell therapy in cardiology: focus on endothelial progenitor cells
R Ferrari, CA Beltrami, L Tavazzi - … & Haematological Disorders …, 2010 - ingentaconnect.com
The crucial role played by the endothelium in cardiovascular disorders has been repetitively
recognised. Endothelium injury has been implicated in atherosclerosis, thrombosis …
recognised. Endothelium injury has been implicated in atherosclerosis, thrombosis …
Endothelial cells regulate physiological cardiomyocyte growth via VEGFR2-mediated paracrine signaling
R Kivelä, KA Hemanthakumar, K Vaparanta… - Circulation, 2019 - Am Heart Assoc
Background: Heart failure, which is a major global health problem, is often preceded by
pathological cardiac hypertrophy. The expansion of the cardiac vasculature, to maintain …
pathological cardiac hypertrophy. The expansion of the cardiac vasculature, to maintain …
Circulating endothelial cells in coronary artery disease and acute coronary syndrome
DE Schmidt, M Manca, IE Hoefer - Trends in cardiovascular medicine, 2015 - Elsevier
Circulating endothelial cells (CECs) have been put forward as a promising biomarker for
diagnosis and prognosis of coronary artery disease and acute coronary syndromes. This …
diagnosis and prognosis of coronary artery disease and acute coronary syndromes. This …
Endothelial progenitor cells in heart failure: an authentic expectation for potential future use and a lack of universal definition
Congestive heart failure (CHF) is a prevalent disease (especially among the elderly) with
high mortality and morbidity rates. The pathological hallmark of CHF is a loss of …
high mortality and morbidity rates. The pathological hallmark of CHF is a loss of …
[HTML][HTML] Endocardial cells form the coronary arteries by angiogenesis through myocardial-endocardial VEGF signaling
B Wu, Z Zhang, W Lui, X Chen, Y Wang… - Cell, 2012 - cell.com
The origins and developmental mechanisms of coronary arteries are incompletely
understood. We show here by fate mapping, clonal analysis, and immunohistochemistry that …
understood. We show here by fate mapping, clonal analysis, and immunohistochemistry that …
Contribution of VEGF-B-induced endocardial endothelial cell lineage in physiological versus pathological cardiac hypertrophy
BACKGROUND: Preclinical studies have shown the therapeutic potential of VEGF-B
(vascular endothelial growth factor B) in revascularization of the ischemic myocardium, but …
(vascular endothelial growth factor B) in revascularization of the ischemic myocardium, but …