Modeling the influence of gravity and the mechanical properties of elastin and collagen fibers on alveolar and lung pressure–volume curves
The relationship between pressure (P) and volume (V) in the human lung has been
extensively studied. However, the combined effects of gravity and the mechanical properties …
extensively studied. However, the combined effects of gravity and the mechanical properties …
Inflation instability in the lung: an analytical model of a thick-walled alveolus with wavy fibres under large deformations
Inflation of hollow elastic structures can become unstable and exhibit a runaway
phenomenon if the tension in their walls does not rise rapidly enough with increasing …
phenomenon if the tension in their walls does not rise rapidly enough with increasing …
Analysis of stress distribution in the alveolar septa of normal and simulated emphysematic lungs
A Gefen, D Elad, RJ Shiner - Journal of biomechanics, 1999 - Elsevier
The alveolar septum consists of a skeleton of fine collagen and elastin fibers, which are
interlaced with a capillary network. Its mechanical characteristics play an important role in …
interlaced with a capillary network. Its mechanical characteristics play an important role in …
Introducing a custom-designed volume-pressure machine for novel measurements of whole lung organ viscoelasticity and direct comparisons between positive-and …
Asthma, emphysema, COVID-19 and other lung-impacting diseases cause the remodeling
of tissue structural properties and can lead to changes in conducting pulmonary volume …
of tissue structural properties and can lead to changes in conducting pulmonary volume …
[HTML][HTML] Lung parenchymal mechanics
The lung parenchyma comprises a large number of thin-walled alveoli, forming an
enormous surface area, which serves to maintain proper gas exchange. The alveoli are held …
enormous surface area, which serves to maintain proper gas exchange. The alveoli are held …
An analytical model for estimating alveolar wall elastic moduli from lung tissue uniaxial stress-strain curves
S Bou Jawde, A Takahashi, JHT Bates… - Frontiers in physiology, 2020 - frontiersin.org
The non-linear stress-strain behavior of uniaxially-stretched lung parenchyma is thought to
be an emergent phenomenon arising from the ensemble behavior of its microscopic …
be an emergent phenomenon arising from the ensemble behavior of its microscopic …
A distributed nonlinear model of lung tissue elasticity
Maksym, Geoffrey N., and Jason HT Bates. A distributed nonlinear model of lung tissue
elasticity. J. Appl. Physiol. 82 (1): 32–41, 1997.—-We present a theory relating the static …
elasticity. J. Appl. Physiol. 82 (1): 32–41, 1997.—-We present a theory relating the static …
Lung parenchymal mechanics in health and disease
DS Faffe, WA Zin - Physiological reviews, 2009 - journals.physiology.org
The mechanical properties of lung tissue are important determinants of lung physiological
functions. The connective tissue is composed mainly of cells and extracellular matrix, where …
functions. The connective tissue is composed mainly of cells and extracellular matrix, where …
[HTML][HTML] Airway-parenchymal interdependence
PD Paré, W Mitzner - Comprehensive physiology, 2012 - ncbi.nlm.nih.gov
In this manuscript we discuss the interaction of the lung parenchyma and the airways as well
as the physiological and pathophysiological significance of this interaction. These two …
as the physiological and pathophysiological significance of this interaction. These two …
The role of three-dimensionality and alveolar pressure in the distribution and amplification of alveolar stresses
MA Sarabia-Vallejos, M Zuñiga, DE Hurtado - Scientific reports, 2019 - nature.com
Alveolar stresses are fundamental to enable the respiration process in mammalians and
have recently gained increasing attention due to their mechanobiological role in the …
have recently gained increasing attention due to their mechanobiological role in the …