Update on the features and measurements of experimental acute lung injury in animals: an official American Thoracic Society workshop report

HS Kulkarni, JS Lee, JA Bastarache… - American journal of …, 2022 - atsjournals.org
Advancements in methods, technology, and our understanding of the pathobiology of lung
injury have created the need to update the definition of experimental acute lung injury (ALI) …

An official American Thoracic Society workshop report: features and measurements of experimental acute lung injury in animals

G Matute-Bello, G Downey, BB Moore… - American journal of …, 2011 - atsjournals.org
Acute lung injury (ALI) is well defined in humans, but there is no agreement as to the main
features of acute lung injury in animal models. A Committee was organized to determine the …

Human models of acute lung injury

AG Proudfoot, DF McAuley… - Disease models & …, 2011 - journals.biologists.com
Acute lung injury (ALI) is a syndrome that is characterised by acute inflammation and tissue
injury that affects normal gas exchange in the lungs. Hallmarks of ALI include dysfunction of …

Resolution of acute lung injury and inflammation: a translational mouse model

BV Patel, MR Wilson, M Takata - European Respiratory Journal, 2012 - Eur Respiratory Soc
Previous animal models of acute lung injury (ALI) are limited as they only reproduce part of
the complex pathobiology of clinical ALI. Here we develop a translational mouse model of …

Biomarkers in acute lung injury: insights into the pathogenesis of acute lung injury

LJM Cross, MA Matthay - Critical care clinics, 2011 - criticalcare.theclinics.com
The ability of the lung to perform gas exchange is made possible in part by the effective
relationship between the alveolar epithelium and the endothelium of the pulmonary …

Acute lung injury and the acute respiratory distress syndrome: four decades of inquiry into pathogenesis and rational management

MA Matthay, GA Zimmerman - American journal of respiratory cell …, 2005 - atsjournals.org
In 2005, the American Thoracic Society marks its 100th year of existence. For over a third of
this span, since 1967, clinicians and investigators have struggled with a common, often …

Future research directions in acute lung injury: summary of a National Heart, Lung, and Blood Institute working group

MA Matthay, GA Zimmerman, C Esmon… - American journal of …, 2003 - atsjournals.org
Acute lung injury (ALI) and its more severe form, the acute respiratory distress syndrome
(ARDS), are syndromes of acute respiratory failure that result from acute pulmonary edema …

Animal models of acute lung injury

G Matute-Bello, CW Frevert… - American Journal of …, 2008 - journals.physiology.org
Acute lung injury in humans is characterized histopathologically by neutrophilic alveolitis,
injury of the alveolar epithelium and endothelium, hyaline membrane formation, and …

Acute lung injury review

K Tsushima, LS King, NR Aggarwal, A De Gorordo… - Internal …, 2009 - jstage.jst.go.jp
The first report of acute respiratory distress syndrome (ARDS) was published in 1967, and
even now acute lung injury (ALI) and ARDS are severe forms of diffuse lung disease that …

Models and mechanisms of acute lung injury caused by direct insults

LK Reiss, U Uhlig, S Uhlig - European journal of cell biology, 2012 - Elsevier
Acute lung injury (ALI) and its more severe form acute respiratory distress syndrome (ARDS)
are life-threatening diseases that are characterized by acute onset, pulmonary inflammation …