Non-heme iron is an important element supporting the structure and functioning of biological
tissues. Imbalance in non-heme iron can lead to different neurological disorders. Several …

For the last century, there has been great physiological interest in brain iron and its role in
brain function and disease. It is well known that iron accumulates in the brain for people with …

Magnetic resonance imaging (MRI) studies have highlighted the possibility to investigate
brain iron content in vivo. In this study, we combined T2* relaxometry and automatic …

Brain iron is a major contributor to magnetic resonance imaging (MRI) contrast in normal
gray matter, and its role in the pathogenesis of different neurological disorders has also …

Background and Purpose Several magnetic resonance imaging (MRI) techniques are being
exploited to measure brain iron levels increasingly as iron deposition has been implicated in …

Objectives: To review published magnetic resonance imaging (MRI) iron quantification
techniques in the context of quantitative MRI and MR relaxation theories. To analyze …

Iron levels in the brain can be estimated using newly developed specific magnetic
resonance imaging (MRI) sequences. This technique has several applications, especially in …

Iron deposition in the human brain tissue occurs in the process of normal aging and in many
neurodegenerative diseases. Elevated iron levels in certain brain regions are also an …

Most studies of brain iron relied on the effect of the iron on magnetic resonance (MR)
relaxation properties, such as R 2∗, and bulk tissue magnetic susceptibility, as measured by …

Magnetic resonance imaging (MRI) enables a noninvasive in vivo quantification of iron in
various organs. Several techniques have been developed that detect signal alterations …