Aims: To compare the lung functions of TOPD phenotype patients and COPD patients other
than TOPD phenotype. Settings and design: Retro-prospective cohort study. Introduction …

Chronic obstructive pulmonary disease (COPD) is diagnosed simply based on the presence
of not fully reversible airflow limitation on post-bronchodilator spirometry. However, there are …

The tuberculosis associated COPD (TOPD)() as a common chronic airway inflammation is
mostly found in elderly patients. TOPD may be prevented and treated in early stage, but in …

Methods We analyzed data from the COPDGene cohort which includes current and former
smokers (age 45-80 years) followed for change in post-bronchodilator FEV1 over five years …

Background: Chronic obstructive pulmonary disease (COPD) remains a major cause of
morbidity and mortality. Present-day diagnostic criteria are largely based solely on …

1. Pellegrino R, Viegi G, Brusasco V, et al. Interpretative strategies for lung function tests. Eur
Respir J 2005; 26: 948–68. 2. Celli BR, MacNee W. Standards for the diagnosis and …

Chronic obstructive pulmonary disease (COPD) is a complex and heterogeneous disease,
and there is a clinical need for validated markers and biomarkers that can contribute to the …

BACKGROUND Pulmonary Function Testing (PFT) is currently used to diagnose and risk
stratify Chronic Obstructive Pulmonary Disease (COPD), and CT imaging can be used in …

In the executive summary of the 2006 update of the Global Initiative for Chronic Obstructive
Lung Disease (GOLD) guidelines (1), the authors state that it is difficult to differentiate …

Background: Previous attempts to explore the heterogeneity of chronic obstructive
pulmonary disease (COPD) clustered individual patients using clinical, demographic, and …