Elevated serum IL-34 is correlated with disease severity in patients with biliary atresia following Kasai portoenterostomy

S Honsawek, N Bovornsethanant, T Woraruthai… - International …, 2024 - Elsevier
Background Biliary atresia (BA) is a severe congenital disorder with progressive obstructive
cholangiopathy in young children. The inflammatory process has been recognized as one of …

Interleukin-33 overexpression is associated with gamma-glutamyl transferase in biliary atresia

R Dong, K Dong, X Wang, G Chen, C Shen, S Zheng - Cytokine, 2013 - Elsevier
Interleukin-33 (IL-33) plays a crucial role in inflammation. However, it is not clear whether IL-
33 levels are of clinical significance for patients with biliary atresia (BA). The purpose of this …

Lower plasma levels of IL-35 in patients with primary biliary cirrhosis

T Li, Y Huang, P Liu, Y Liu, J Guo, W Zhang… - The Tohoku Journal of …, 2018 - jstage.jst.go.jp
Primary biliary cirrhosis (PBC) is an autoimmune liver disease. Its histological
characteristics, such as progressive intrahepatic bile duct destruction, cholestasis, and liver …

[HTML][HTML] Correlation of interleukin-33/ST2 receptor and liver fibrosis progression in biliary atresia patients

J Liu, YF Yang, C Zheng, G Chen, Z Shen… - Frontiers in …, 2019 - frontiersin.org
Background/Aims: Biliary Atresia (BA) is a devastating pediatric liver disease and
characterized by aggressive liver fibrosis progression. The Interleukin-33 (IL-33)/ST2 …

[HTML][HTML] Preoperative serum IL-12p40 is a potential predictor of kasai portoenterostomy outcome in infants with biliary atresia

SS Goda, MA Khedr, SZ Elshenawy… - … Research and Practice, 2017 - hindawi.com
The standard-of-care treatment for biliary atresia (BA) is surgical restoration of bile flow by
Kasai portoenterostomy. We aimed to study serum interleukin-(IL-) 12p40, a natural …

Implication of increased serum IL-31 for primary biliary cholangitis

N Mu, F Lin, Z Jiang, Y Liang, Z Yang - Immunological …, 2021 - Taylor & Francis
ABSTRACT Interleukin-31 (IL-31) has diverse biological functions. Increased IL-31 has been
found in some skin and autoimmune diseases. There has been no study reporting the …

Interleukin 17, produced by γδ T cells, contributes to hepatic inflammation in a mouse model of biliary atresia and is increased in livers of patients

C Klemann, A Schröder, A Dreier, N Möhn, S Dippel… - Gastroenterology, 2016 - Elsevier
Background & Aims Biliary atresia (BA) is a rare disease in infants, with unknown
mechanisms of pathogenesis. It is characterized by hepatobiliary inflammatory, progressive …

Clinical value of serum interleukin-33 biomarker in infants with neonatal cholestasis

OG Behairy, AE Elsadek, EG Behiry… - Journal of Pediatric …, 2020 - journals.lww.com
Objectives: The present study aimed to estimate the value of serum interleukin-33 (IL-33)
levels in infants with cholestasis, correlate serum IL-33 levels with the clinicopathological …

Serum level of interleukin-13 receptor alpha 2 in infants with biliary atresia–is it of value?

N Adawy, H El-Araby, A Allam, S Elshenawy… - Clinical and …, 2018 - termedia.pl
Results The mean value of IL-13Rα2 was significantly higher in delayed BA group
(11.05±10.9 ng/ml) compared to early BA (0.34±0.37 ng/ml), non-BA (0.54±0.85 ng/ml) and …

Biliary repair and carcinogenesis are mediated by IL-33–dependent cholangiocyte proliferation

J Li, N Razumilava, GJ Gores, S Walters… - The Journal of …, 2014 - Am Soc Clin Investig
Injury to the biliary epithelium triggers inflammation and fibrosis, which can result in severe
liver diseases and may progress to malignancy. Development of a type 1 immune response …