A high serum interleukin‐12p40 level prior to Kasai surgery predict a favourable outcome in children with biliary atresia

JF Wu, PC Kao, HL Chen, HS Lai, HY Hsu… - Liver …, 2012 - Wiley Online Library
Background Biliary atresia (BA) is a paediatric cholestatic disease characterized by a
progressive fibro‐inflammation of the biliary tree. Current treatment of choice is to establish …

Interleukin-17A plays a pivotal role in cholestatic liver fibrosis in mice

M Hara, H Kono, S Furuya, K Hirayama… - Journal of Surgical …, 2013 - Elsevier
Background It was recently reported that serum interleukin (IL)-17 levels increased in liver
fibrosis associated with human alcoholic liver disease. However, the role of IL-17 in liver …

Study of interleukin-22 in patients with liver cirrhosis in Menoufia University Hospitals, Egypt

AEH Dawoud, M Amal, AZ Labib… - Menoufia Medical …, 2015 - menoufia-med-j.com
Objectives The aims of the study were to determine serum levels of interleukin-22 (IL-22) in
patients with liver cirrhosis in Menoufia University Hospitals and to detect its relation with the …

Protective effect of Th22 cells and intrahepatic IL-22 in drug induced hepatocellular injury

R Lai, X Xiang, R Mo, R Bao, P Wang, S Guo… - Journal of …, 2015 - Elsevier
Background & Aims Th22 cells regulate host immunity against pathogenic invasion,
including protecting host against chronic hepatitis B; however, the relationship between drug …

Interleukin-33 promotes disease progression in patients with primary biliary cirrhosis

Y Sun, JY Zhang, S Lv, H Wang, M Gong… - The Tohoku Journal of …, 2014 - jstage.jst.go.jp
Primary biliary cirrhosis (PBC) is a progressive autoimmune liver disease that can cause a
series of complications, including cirrhosis, liver failure and hepatocellular carcinoma …

Loss of interleukin-12 modifies the pro-inflammatory response but does not prevent duct obstruction in experimental biliary atresia

SK Mohanty, P Shivakumar, G Sabla, JA Bezerra - BMC gastroenterology, 2006 - Springer
Background Livers of infants with biliary atresia and of neonatal mice infected with rotavirus
(RRV) have increased expression of interferon-gamma (IFNγ) and interleukin (IL)-12. While …

Interleukin-34 is more suitable than macrophage colony-stimulating factor for predicting liver significant fibrosis in patients with chronic hepatitis B

K Yang, P Ying, B Sun - Scandinavian Journal of Gastroenterology, 2024 - Taylor & Francis
Abstract Aims Interleukin-34 (IL-34) and macrophage colony-stimulating factor (CSF-1) have
similar functions, such as promoting the formation of liver fibrosis. This study aimed to …

[HTML][HTML] The expression and clinical significance of serum IL-17 in patients with primary biliary cirrhosis

Q Sun, Q Wang, N Feng, Y Meng, B Li… - Annals of …, 2019 - ncbi.nlm.nih.gov
Background We aimed to investigate the expression and clinical significance of interleukin
17 (IL-17) in patients with primary biliary cirrhosis (PBC). Methods PBC patients (n= 127) …

Interleukin‐8: a critical chemokine in biliary atresia

R Dong, S Zheng - Journal of gastroenterology and hepatology, 2015 - Wiley Online Library
Biliary atresia (BA) is characterized by periductular inflammation and fibrosis and is
associated with the progressive obliteration of the bile ducts. The induction and …

Combination of IL-34 and AFP improves the diagnostic value during the development of HBV related hepatocellular carcinoma

K Liu, Y Ding, Y Wang, Q Zhao, L Yan, J Xie… - Clinical and …, 2023 - Springer
IL-34 involves in host immunity regulated carcinogenesis. Alpha-fetoprotein (AFP) is related
to the development of HCC. We explored if combination of IL-34 and APF could improve the …