Background & Aims: Liver fibrosis is a common consequence of chronic liver injury and is
characterized by the accumulation of extracellular matrix mainly generated from activated …

MicroRNAs (miRNAs) are small, non-coding RNAs that negatively regulate target mRNA
expression, and altered expression of miRNAs is associated with liver pathological …

BACKGROUND Activation of hepatic stellate cells (HSCs) is a pivotal event in the onset and
progression of liver fibrosis. Loss of microRNA-194 (miR-194) has been reported in …

Liver fibrosis is a common pathological process of end-stage liver diseases. However, the
role of microRNA (miRNA) in liver fibrosis is poorly understood. The activated hepatic …

Hepatic fibrosis is a chronic inflammatory and reversible repair reaction of the liver under the
continuous action of virus or various injuries. In this study, we aimed at identifying the role of …

Liver fibrosis is a chronic liver disease characterized by the proliferation and activation of
hepatic stellate cells (HSCs) and excessive deposition of extracellular matrix (ECM) …

There has been an increasing number of researches about microRNAs (miRNAs) in the
progression of liver fibrosis from the point of their comprehensive functions in regulating the …

Background & Aims Fibrosis, a cardinal feature of a dysfunctional liver, significantly
contributes to the ever-increasing mortality due to end-stage chronic liver diseases. The …

Recent studies have shown the effect of microRNAs on HSC activation and transformation,
which is essential for the pathogenesis of liver fibrosis. In our study, we explored the role of …

Persistent hepatic damage and chronic inflammation in liver activate the quiescent hepatic
stellate cells (HSCs) and cause hepatic fibrosis (HF). Several microRNAs regulate the …