The potential transient vanilloid receptor type 1 (TRPV1) plays important functional roles in
the vascular system. In the present study, we explored the role of the TRPV1 in the …

Aims We investigated the role of transient receptor potential vanilloid receptor type 1
(TRPV1) in simvastatin‐mediated activation of endothelial nitric oxide synthase (eNOS) and …

Background and aims Transient receptor potential vanilloid type 1 channel (TRPV1) is found
to be expressed in endothelial cells (ECs) and activate endothelial nitric oxide synthase …

The endothelium contributes to the maintenance of vasodilator tone by releasing
endothelium-derived relaxing factors, including nitric oxide (NO). In hypertension …

Antioxidative stress provides a cardioprotective effect during myocardial
ischemia/reperfusion (I/R). Previous research has demonstrated that the blockade of …

Aims We investigated the molecular mechanism underlying the role of transient receptor
potential vanilloid type 1 (TRPV1), a Ca2+-permeable non-selective cation channel, in the …

The role of TRPV4 (transient receptor potential vanilloid 4) in regulating vascular contraction
in hypertensive mice is poorly established. We tested the hypothesis that TRPV4 regulates …

Aims Transient receptor potential vanilloid 2 (TRPV2) channels are expressed in both
smooth muscle and endothelial cells and participate in vascular mechanotransduction and …

Shear stress stimulates nitric oxide (NO) release in endothelial cells. Stretch-activated ion
channels (SACs) and the transient receptor potential vanilloid type 1 (TRPV1) receptor …

Transient receptor potential vanilloid 4 (TRPV4) channels are widely expressed in systemic
tissues and can be activated by many stimuli. TRPV4, a Ca2+-permeable cation channel …