Safety and immunogenicity of a tetravalent and bivalent SARS-CoV-2 protein booster vaccine in men

S Hannawi, L Saf Eldin, A Abuquta, A Alamadi… - Nature …, 2023 - nature.com
The safety and immunogenicity of a protein-based tetravalent vaccine SCTV01E that
contains spike protein ectodomain (S-ECD) of Alpha, Beta, Delta and Omicron BA. 1 are …

Safety and immunogenicity of a bivalent SARS-CoV-2 protein booster vaccine, SCTV01C, in adults previously vaccinated with mRNA vaccine: A randomized, double …

S Hannawi, LS Eldin, A Abuquta, A Alamadi… - …, 2023 - thelancet.com
Background Booster vaccination is an efficient way to address the waning protection of
vaccines and immune escape of SARS-CoV-2 variants. We aimed to assess the safety and …

[HTML][HTML] What defines an efficacious COVID-19 vaccine? A review of the challenges assessing the clinical efficacy of vaccines against SARS-CoV-2

SH Hodgson, K Mansatta, G Mallett, V Harris… - The lancet infectious …, 2021 - thelancet.com
The novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),
has caused more than 1 million deaths in the first 6 months of the pandemic and huge …

Randomized, double-blinded and placebo-controlled phase II trial of an inactivated SARS-CoV-2 vaccine in healthy adults

Y Che, X Liu, Y Pu, M Zhou, Z Zhao… - … diseases: an official …, 2020 - ncbi.nlm.nih.gov
Background We evaluated an inactivated SARS-CoV-2 vaccine for immunogenicity and
safety in adults aged 18-59 years. Methods In this randomized, double-blinded and …

Interim results of a phase 1–2a trial of Ad26. COV2. S Covid-19 vaccine

J Sadoff, M Le Gars, G Shukarev… - … England Journal of …, 2021 - Mass Medical Soc
Background Efficacious vaccines are urgently needed to contain the ongoing coronavirus
disease 2019 (Covid-19) pandemic of infection with severe acute respiratory syndrome …

Pfizer-BioNTech and Oxford AstraZeneca COVID-19 vaccine effectiveness and immune response amongst individuals in clinical risk groups

HJ Whitaker, RSM Tsang, R Byford, NJ Andrews… - Journal of Infection, 2022 - Elsevier
Background COVID-19 vaccines approved in the UK are highly effective in general
population cohorts, however, data on effectiveness amongst individuals with clinical …

Efficacy and safety of an inactivated whole-virion SARS-CoV-2 vaccine (CoronaVac): interim results of a double-blind, randomised, placebo-controlled, phase 3 trial in …

MD Tanriover, HL Doğanay, M Akova, HR Güner… - The Lancet, 2021 - thelancet.com
Background CoronaVac, an inactivated whole-virion SARS-CoV-2 vaccine, has been shown
to be well tolerated with a good safety profile in individuals aged 18 years and older in …

Response to additional COVID-19 vaccine doses in people who are immunocompromised: a rapid review

EPK Parker, S Desai, M Marti, H Nohynek… - The Lancet Global …, 2022 - thelancet.com
Individuals with compromised immune systems, whether because of immunodeficiency or
immuno suppressive therapy, are among those most susceptible to COVID19. In fact, people …

Immunogenicity, safety, and reactogenicity of heterologous COVID-19 primary vaccination incorporating mRNA, viral-vector, and protein-adjuvant vaccines in the UK …

ASV Stuart, RH Shaw, X Liu, M Greenland, PK Aley… - The Lancet, 2022 - thelancet.com
Background Given the importance of flexible use of different COVID-19 vaccines within the
same schedule to facilitate rapid deployment, we studied mixed priming schedules …

[HTML][HTML] Risk of infection, hospitalisation, and death up to 9 months after a second dose of COVID-19 vaccine: a retrospective, total population cohort study in Sweden

P Nordström, M Ballin, A Nordström - The Lancet, 2022 - thelancet.com
Background Vaccine effectiveness against COVID-19 beyond 6 months remains
incompletely understood. We aimed to investigate the effectiveness of COVID-19 …