Safety and immunogenicity of an AS03-adjuvanted plant-based SARS-CoV-2 vaccine in Adults with and without Comorbidities

N Charland, P Gobeil, S Pillet, I Boulay, A Séguin… - npj Vaccines, 2022 - nature.com
The rapid spread of SARS-CoV-2 continues to impact humanity on a global scale with rising
total morbidity and mortality. Despite the development of several effective vaccines, new …

Immunogenicity, durability, and safety of an mRNA and three platform-based COVID-19 vaccines as a third dose following two doses of CoronaVac in China: a …

Y Zhang, X Ma, G Yan, Y Wu, Y Chen, Z Zhou… - …, 2022 - thelancet.com
Background More effective vaccine candidates against variants of concern as a booster
dose are needed in people primed with two-dose inactivated COVID-19 vaccines. Methods …

Immunological and clinical efficacy of COVID-19 vaccines in immunocompromised populations: a systematic review

S Galmiche, LBL Nguyen, E Tartour… - Clinical Microbiology …, 2022 - Elsevier
Background Available data show that COVID-19 vaccines may be less effective in
immunocompromised populations, who are at increased risk of severe COVID-19 …

Safety and immunogenicity of aerosolised Ad5-nCoV, intramuscular Ad5-nCoV, or inactivated COVID-19 vaccine CoronaVac given as the second booster following …

R Tang, H Zheng, BS Wang, JB Gou… - The Lancet …, 2023 - thelancet.com
Summary Background Aerosolised Ad5-nCoV is the first approved mucosal respiratory
COVID-19 vaccine to be used as a booster after the primary immunisation with COVID-19 …

Third dose of SARS‐CoV‐2 vaccine: A systematic review of 30 published studies

F Petrelli, A Luciani, K Borgonovo… - Journal of Medical …, 2022 - Wiley Online Library
We analyzed published studies on the efficacy and safety of the third dose of the COVID‐19
vaccine in various general population settings. We conducted systematic searches of …

Current clinical trials protocols and the global effort for immunization against SARS-CoV-2

GNA Rego, MP Nucci, AH Alves, FA Oliveira, LC Marti… - Vaccines, 2020 - mdpi.com
Coronavirus disease 2019 (COVID-19) is the biggest health challenge of the 21st century,
affecting millions of people globally. The outbreak of severe acute respiratory syndrome …

Prospective evaluation of coronavirus disease 2019 (COVID-19) vaccine responses across a broad spectrum of immunocompromising conditions: the COVID-19 …

G Haidar, M Agha, A Bilderback… - Clinical Infectious …, 2022 - academic.oup.com
Background We studied humoral responses after coronavirus disease 2019 (COVID-19)
vaccination across varying causes of immunodeficiency. Methods Prospective study of fully …

Vaccine effectiveness against SARS-CoV-2 infection or COVID-19 hospitalization with the Alpha, Delta, or Omicron SARS-CoV-2 variant: A nationwide Danish cohort …

MA Gram, HD Emborg, AB Schelde, NU Friis… - PLoS …, 2022 - journals.plos.org
Background The continued occurrence of more contagious Severe Acute Respiratory
Syndrome Coronavirus 2 (SARS-CoV-2) variants and waning immunity over time require …

COVID-19 vaccine effectiveness among immunocompromised populations: a targeted literature review of real-world studies

M Di Fusco, J Lin, S Vaghela… - Expert Review of …, 2022 - Taylor & Francis
ABSTRACT Introduction From July through October of 2021, several countries issued
recommendations for increased COVID-19 vaccine protection for individuals with one or …

First-in-human use of a modular capsid virus-like vaccine platform: an open-label, non-randomised, phase 1 clinical trial of the SARS-CoV-2 vaccine ABNCoV2

MJ Smit, AF Sander, MBPA Ariaans… - The Lancet …, 2023 - thelancet.com
Background Capsid virus-like particles (cVLP) have proven safe and immunogenic and can
be a versatile platform to counter pandemics. We aimed to clinically test a modular cVLP …