Association of prenatal exposure to antiseizure medication with risk of autism and intellectual disability

MH Bjørk, H Zoega, MK Leinonen, JM Cohen… - JAMA …, 2022 - jamanetwork.com
Importance Women with epilepsy frequently need antiseizure medication (ASM) to prevent
seizures in pregnancy. Risk of neurodevelopmental disorders after prenatal exposure to …

Prenatal exposure to antiseizure medication and incidence of childhood-and adolescence-onset psychiatric disorders

JW Dreier, MH Bjørk, S Alvestad, M Gissler… - JAMA …, 2023 - jamanetwork.com
Importance Prenatal antiseizure medication (ASM) exposure has been associated with
adverse early neurodevelopment, but associations with a wider range of psychiatric end …

Antiseizure medication use during pregnancy and risk of ASD and ADHD in children

KK Wiggs, ME Rickert, AC Sujan, PD Quinn… - Neurology, 2020 - AAN Enterprises
Objective To determine whether children born to women who use antiseizure medications
(ASMs) during pregnancy have higher risk of autism spectrum disorder (ASD) and attention …

Two-year-old cognitive outcomes in children of pregnant women with epilepsy in the maternal outcomes and neurodevelopmental effects of antiepileptic drugs study

KJ Meador, MJ Cohen, DW Loring, RC May… - JAMA …, 2021 - jamanetwork.com
Importance The neurodevelopmental risks of fetal exposure are uncertain for many
antiseizure medications (ASMs). Objective To compare children at 2 years of age who were …

Association between pregnancy and perinatal outcomes among women with epilepsy

N Razaz, T Tomson, AK Wikström… - JAMA neurology, 2017 - jamanetwork.com
Importance To date, few attempts have been made to examine associations between
exposure to maternal epilepsy with or without antiepileptic drug (AED) therapy and …

Fetal growth and premature delivery in pregnant women on antiepileptic drugs

S Hernández‐Díaz, TF McElrath, PB Pennell… - Annals of …, 2017 - Wiley Online Library
Objective To evaluate the effects of epilepsy and antiepileptic drugs (AEDs) used during
pregnancy on fetal growth and preterm delivery. Methods This study included singleton …

Cognitive outcomes at age 3 years in children with fetal exposure to antiseizure medications (MONEAD study) in the USA: a prospective, observational cohort study

KJ Meador, MJ Cohen, DW Loring… - The Lancet …, 2023 - thelancet.com
Background The neurodevelopmental effects of fetal exposure to most antiseizure
medications are unclear. We aimed to investigate the effects of fetal exposure to commonly …

Antiseizure medication concentrations during pregnancy: results from the maternal outcomes and neurodevelopmental effects of antiepileptic drugs (MONEAD) study

PB Pennell, A Karanam, KJ Meador, E Gerard… - JAMA …, 2022 - jamanetwork.com
Importance During pregnancy in women with epilepsy, lower blood concentrations of
antiseizure medications can have adverse clinical consequences. Objective To characterize …

Risks of 23 specific malformations associated with prenatal exposure to 10 antiepileptic drugs

PO Blotière, F Raguideau, A Weill, E Elefant, I Perthus… - Neurology, 2019 - AAN Enterprises
Objective To assess the association between exposure to monotherapy with 10 different
antiepileptic drugs (AEDs) during the first 2 months of pregnancy and the risk of 23 major …

Prospective assessment of autism traits in children exposed to antiepileptic drugs during pregnancy

AG Wood, C Nadebaum, V Anderson, D Reutens… - …, 2015 - Wiley Online Library
Purpose The association between autism spectrum disorders (ASD s) and prenatal
anticonvulsant exposure is increasingly investigated, but comprehensive, blinded …