Intraperitoneal BromAc® Does Not Interfere with the Healing of Colon Anastomosis
AH Mekkawy, M Breakeit, K Pillai, S Badar, J Akhter… - Cancers, 2023 - mdpi.com
Simple Summary The drug BromAc® has been used in the treatment of pseudomyxoma
peritonei, a rare peritoneal cancer. Often, patients with pseudomyxoma peritonei require …
peritonei, a rare peritoneal cancer. Often, patients with pseudomyxoma peritonei require …
A formulation for in situ lysis of mucin secreted in pseudomyxoma peritonei
K Pillai, J Akhter, TC Chua… - International journal of …, 2014 - Wiley Online Library
Although numerous clinical attempts have been made to disintegrate mucin secreted by
pseudomyxoma peritonei (PMP), none are clinically recommended. Through examination of …
pseudomyxoma peritonei (PMP), none are clinically recommended. Through examination of …
Mucolysis by ascorbic acid and hydrogen peroxide on compact mucin secreted in pseudomyxoma peritonei
K Pillai, J Akhter, TC Chua, DL Morris - Journal of Surgical research, 2012 - Elsevier
BACKGROUND: This study examines the potential efficacy of hydrogen peroxide and
ascorbic acid in the dissolution of mucinous ascites from pseudomyxoma peritonei …
ascorbic acid in the dissolution of mucinous ascites from pseudomyxoma peritonei …
Intratumoral Bromelain and Acetylcysteine for Recurrent and Unresectable Pseudomyxoma Peritonei. A Phase I/II, unicentric study.
LR Ortiz, AR Ruiz, JMS Hidalgo, ÁC Adam… - European Journal of …, 2022 - ejso.com
Background: Mucinous neoplasms with peritoneal spread constitute an infrequent entity
known as Pseudomyxoma Peritonei. The massive intraabdominal affectation contrast with …
known as Pseudomyxoma Peritonei. The massive intraabdominal affectation contrast with …
The effect of intraperitoneal administration of BromAc on blood parameters: phase 1 study
K Ke, K Pillai, AH Mekkawy, J Akhter, S Badar… - Discover Oncology, 2021 - Springer
Intraperitoneal administration of BromAc (bromelain+ acetylcysteine) is currently undergoing
a phase 1 clinical trial for pseudomyxoma peritonei at our institution. This study reports on …
a phase 1 clinical trial for pseudomyxoma peritonei at our institution. This study reports on …
Intra-tumoural bromelain and N-acetylcysteine for recurrent and unresectable pseudomyxoma peritonei: phase I/II trial
L Rodríguez-Ortiz, MC Vázquez-Borrego… - British Journal of …, 2024 - academic.oup.com
Pseudomyxoma peritonei (PMP) is considered a rare disease caused by mucin-secreting
tumour cells commonly arising from the appendix 1. Cytoreductive surgery plus …
tumour cells commonly arising from the appendix 1. Cytoreductive surgery plus …
Chronic anti-inflammatory drug therapy inhibits gel-forming mucin production in a murine xenograft model of human pseudomyxoma peritonei
Background Intraperitoneal accumulation of mucinous ascites in pseudomyxoma peritonei
(PMP) promotes an inflammatory/fibrotic reaction that progresses to bowel obstruction and …
(PMP) promotes an inflammatory/fibrotic reaction that progresses to bowel obstruction and …
Quality of life after cytoreductive surgery plus early intraperitoneal postoperative chemotherapy for pseudomyxoma peritonei: a prospective study
P Jess, LH Iversen, MB Nielsen, F Hansen… - Diseases of the colon …, 2008 - journals.lww.com
Purpose: The modern treatment of pseudomyxoma peritonei is cytoreductive surgery plus
intraperitoneal chemotherapy resulting in a survival of up to 70 percent after 20 years. The …
intraperitoneal chemotherapy resulting in a survival of up to 70 percent after 20 years. The …
Effective use of bromelain and acetylcysteine (BromAc®) for treatment of perigastric pseudomyxoma peritonei: a case report
E Skalkos, KL Chen, R Wijayawardana… - Anticancer …, 2023 - ar.iiarjournals.org
Background/Aim: Pseudomyxoma peritonei (PMP) is a rare clinical condition of progressive
peritoneal mucin accumulation. PMP has a reasonable survivability but with a notable risk of …
peritoneal mucin accumulation. PMP has a reasonable survivability but with a notable risk of …
The effects of irinotecan on the healing of colonic anastomoses in rats
MG Pramateftakis, D Kanellos, I Kanellos… - The Open Surgery …, 2007 - benthamopen.com
Aim: The aim of this experimental study was to investigate the effects of intraperitoneally
injected irinotecan on the healing of colonic anastomoses after colon resection. Methods …
injected irinotecan on the healing of colonic anastomoses after colon resection. Methods …