Background Tuberculosis (TB) is an infectious disease and its mortality rate ranks first.
Latent tuberculosis infection (LTBI) means that a patient is infected with Mycobacterium …

SETTING: A third of the world's population has latent tuberculous infection (LTBI). Current TB
diagnostics used in developing countries are ineffective and are unable to distinguish LTBI …

Background Cytokines play an important role in cell-mediated immune responses against
Mycobacterium tuberculosis (Mtb) infection. Cytokine profile specifically associated with …

We used the Luminex Bead Array Multiplex Immunoassay to measure cytokines,
chemokines and growth factors responses to the same antigens used for RD1-based …

The host immune response, apart from mycobacterial factors, is a significant determinant in
the development of tuberculosis (TB). The purpose of the study was to examine whether the …

Background: Cytokines, as key regulators of immune responses, are imbalanced in
tuberculosis (TB) which may reflect the status of the disease. Therefore, cytokines could be …

Differentiation of latent tuberculosis infection (LTBI) from active disease is one of the crucial
elements in the control of tuberculosis. Earlier in Indian population which is tuberculosis …

Background Latent tuberculosis infection (LTBI) is a huge reservoir for the deadlier TB
disease. Accurate identification of LTBI is a key strategy to eliminate TB. Therefore, a …

Interferon gamma release assays (IGRAs) have been widely used to diagnose
Mycobacterium tuberculosis (MTB) infection. However, IGRAs cannot discriminate between …

Background Tubercular lymphadenitis (TL) is the most common form of extra-pulmonary
tuberculosis (TB) consisting about 15–20% of all TB cases. The currently available …