NADPH oxidase-dependent superoxide (O2·–) production and oxidative stress play
important roles in endothelial dysfunction and atherosclerosis. Herein, we investigated the …

Reactive oxygen species (ROS) have emerged as important molecules in cardiovascular
function. Nicotinamide-adenine dinucleotide phosphate (NADPH) oxidase is the major …

Several lines of evidence indicate that quercetin, a polyphenol derived in the diet from fruit
and vegetables, contributes to cardiovascular health. We aimed to investigate the effects of …

Myeloperoxidase (MPO) exhibits a unique property to use H2O2 to oxidize chloride and lead
to the generation of a strong oxidant, hypochlorous acid (HOCl), which plays important roles …

Objective—Animal and clinical studies have suggested that polyphenols in fruits, red wine,
and tea may delay the development of atherosclerosis through their antioxidant and anti …

Background and Aims Endothelial senescence is an important risk factor leading to
atherosclerosis. The mechanism of quercetin against endothelial senescence is worth …

Quercetin, the most abundant dietary flavonol, exerts antioxidant effects reducing vascular
superoxide (O2−) and improving endothelial function in animal models of cardiovascular …

Quercetin is a widely known and biologically active phytochemical and exerts therapeutic
effects against atherosclerosis. The removal of senescent plaque macrophages effectively …

Oxidative stress plays an important role in the pathogenesis of cardiovascular disease.
Quercetin, a naturally occurring flavonoid presents in plants and human diet, has been …

Myeloperoxidase (MPO)-dependent hypochlorous acid (HOCl) generation plays crucial
roles in diabetic vascular complications. As a natural polyphenol, quercetin has antioxidant …