CNS imaging characteristics in fibromyalgia patients with and without peripheral nerve involvement

HC Aster, D Evdokimov, A Braun, N Üçeyler, T Kampf… - Scientific reports, 2022 - nature.com
We tested the hypothesis that reduced skin innervation in fibromyalgia syndrome is
associated with specific CNS changes. This prospective case–control study included 43 …

Alterations of brain activity in fibromyalgia patients

P Sawaddiruk, S Paiboonworachat… - Journal of Clinical …, 2017 - Elsevier
Fibromyalgia is a chronic pain syndrome, characterized by widespread musculoskeletal
pain with diffuse tenderness at multiple tender points. Despite intense investigations, the …

[PDF][PDF] Altered whole brain functional activity in patients with fibromyalgia

A Liu, H Jiang, Y Li, Z Jiang… - Clinical and …, 2024 - clinexprheumatol.org
Objective Fibromyalgia (FM) is a chronic pain disorder that takes a severe physical and
psychological toll on patients and severely reduces their quality of life. In recent years, an …

Reduction of skin innervation is associated with a severe fibromyalgia phenotype

D Evdokimov, J Frank, A Klitsch… - Annals of …, 2019 - Wiley Online Library
Objective To assess patterns and impact of small nerve fiber dysfunction and pathology in
patients with fibromyalgia syndrome (FMS). Methods One hundred seventeen women with …

Decreased gray matter volumes in the cingulo-frontal cortex and the amygdala in patients with fibromyalgia

M Burgmer, M Gaubitz, C Konrad… - Psychosomatic …, 2009 - journals.lww.com
Objective: Studies in fibromyalgia syndrome with functional neuroimaging support the
hypothesis of central pain augmentation. To determine whether structural changes in areas …

Neurobiologic features of fibromyalgia are also present among rheumatoid arthritis patients

N Basu, CM Kaplan, E Ichesco, T Larkin… - Arthritis & …, 2018 - Wiley Online Library
Objective Many patients with rheumatoid arthritis (RA) report pain despite excellent control
of inflammation with immunotherapies. Variable degrees of coexisting fibromyalgia (FM) …

Functional connectivity associated with attention networks differs among subgroups of fibromyalgia patients: an observational case–control study

T Aoe, R Kawanaka, F Ohsone, A Hara… - Scientific Reports, 2024 - nature.com
Fibromyalgia is a heterogenous chronic pain disorder diagnosed by symptom-based criteria.
The aim of this study was to clarify different pathophysiological characteristics between …

Striatal grey matter increase in patients suffering from fibromyalgia–a voxel-based morphometry study

T Schmidt-Wilcke, R Luerding, T Weigand, T Jürgens… - Pain, 2007 - Elsevier
Fibromyalgia (FM), among other chronic pain syndromes, such as chronic tension type
headache and atypical face pain, is classified as a so-called dysfunctional pain syndrome …

[HTML][HTML] Three weeks of exercise therapy altered brain functional connectivity in fibromyalgia inpatients

S Kan, N Fujita, M Shibata, K Miki, M Yukioka… - Neurobiology of Pain, 2023 - Elsevier
Background Fibromyalgia (FM) is a chronic pain syndrome characterized by widespread
pain, tenderness, and fatigue. Patients with FM have no effective medication so far, and their …

A systematic review and meta-analysis of voxel-based morphometric studies of fibromyalgia

M Xin, Y Qu, X Peng, D Zhu, S Cheng - Frontiers in Neuroscience, 2023 - frontiersin.org
Objective Although neuroimaging investigations have revealed significant changes in brain
structure in fibromyalgia (FM) patients, these findings are inconsistent. The current study …