A novel therapeutic strategy for hepatocellular carcinoma: Immunomodulatory mechanisms of selenium and/or selenoproteins on a shift towards anti-cancer

BK Wu, QH Chen, D Pan, B Chang, LX Sang - International …, 2021 - Elsevier
Selenium (Se) is an essential trace chemical element that is widely distributed worldwide.
Se exerts its immunomodulatory and nutritional activities in the human body in the form of …

[HTML][HTML] Selenium stimulates the antitumour immunity: Insights to future research

A Razaghi, M Poorebrahim, D Sarhan… - European Journal of …, 2021 - Elsevier
Selenium is an essential trace element for regulating immune functions through redox-
regulating activity of selenoproteins (eg glutathione peroxidase), protecting immune cells …

The functions of selenium and selenoproteins relating to the liver diseases

N Shang, X Wang, Q Shu, H Wang… - Journal of nanoscience …, 2019 - ingentaconnect.com
Selenium is an important trace element. Many studies have proved that selenium can protect
liver tissues by reducing response of immune inflammation and inducing high levels of ROS …

Evaluation of selenite effects on selenoproteins and cytokinome in human hepatoma cell lines

F Rusolo, B Pucci, G Colonna, F Capone, E Guerriero… - Molecules, 2013 - mdpi.com
The need to explore new alternative therapeutic strategies and chemoprevention methods
for hepatocellular carcinoma is growing significantly. Selenium is a trace element that plays …

Selenium in the prevention and treatment of hepatocellular carcinoma

AS Darvesh, A Bishayee - Anti-Cancer Agents in Medicinal …, 2010 - ingentaconnect.com
Hepatocellular carcinoma (HCC) happens to be one of the most lethal cancers in the world.
Even though most cases occur in the developing world, reported cases in Western Europe …

Selenium in oncology: from chemistry to clinics

O Micke, L Schomburg, J Buentzel, K Kisters… - Molecules, 2009 - mdpi.com
The essential trace element selenium, which is a crucial cofactor in the most important
endogenous antioxidative systems of the human body, is attracting more and more the …

Selenoprotein deficiency and high levels of selenium compounds can effectively inhibit hepatocarcinogenesis in transgenic mice

SV Novoselov, DF Calvisi, VM Labunskyy, VM Factor… - Oncogene, 2005 - nature.com
The micronutrient element selenium (Se) has been shown to be effective in reducing the
incidence of cancer in animal models and human clinical trials. Selenoproteins and low …

Selenium or no selenium-that is the question in tumor patients: a new controversy

R Muecke, L Schomburg, J Buentzel… - Integrative Cancer …, 2010 - journals.sagepub.com
The essential trace element selenium, which is a crucial cofactor in the most important
endogenous antioxidative systems of the human body, is attracting more attention from both …

Selenium and selenoproteins in health

F Zhang, X Li, Y Wei - Biomolecules, 2023 - mdpi.com
Selenium is a trace mineral that is essential for health. After being obtained from food and
taken up by the liver, selenium performs various physiological functions in the body in the …

Toward improved human health: Efficacy of dietary selenium on immunity at the cellular level

X Xia, X Zhang, M Liu, M Duan, S Zhang, X Wei… - Food & function, 2021 - pubs.rsc.org
Selenium, an essential trace element in the body, participates in various biological
processes in the form of selenoproteins. In humans, a suitable concentration of selenium is …