Substitutions near the HA receptor binding site explain the origin and major antigenic change of the B/Victoria and B/Yamagata lineages
ME Rosu, P Lexmond, TM Bestebroer… - Proceedings of the …, 2022 - National Acad Sciences
Influenza B virus primarily infects humans, causing seasonal epidemics globally. Two
antigenic variants—Victoria-like and Yamagata-like—were detected in the 1980s, of which …
antigenic variants—Victoria-like and Yamagata-like—were detected in the 1980s, of which …
Antigenic variants with amino acid deletions clarify a neutralizing epitope specific for influenza B virus Victoria group strains
N Nakagawa, R Kubota… - Journal of General …, 2001 - microbiologyresearch.org
To study the neutralizing epitopes of influenza B virus Victoria group strains, two monoclonal
antibodies (MAbs) were used to select antigenic variants of the virus. MAbs 10B8 and 8E6 …
antibodies (MAbs) were used to select antigenic variants of the virus. MAbs 10B8 and 8E6 …
Antigenic and genetic characterization of the haemagglutinins of recent cocirculating strains of influenza B virus
PA Rota, ML Hemphill, T Whistler… - Journal of General …, 1992 - microbiologyresearch.org
The antigenic and genetic characteristics of the haemagglutinins of influenza type B viruses
isolated since 1988 during periods of both widespread activity (1990/1991) and sporadic …
isolated since 1988 during periods of both widespread activity (1990/1991) and sporadic …
Neutralizing epitopes specific for influenza B virus Yamagata group strains are in the 'loop'
N Nakagawa, R Kubota… - Journal of general …, 2003 - microbiologyresearch.org
To study the neutralizing epitopes of influenza B virus Yamagata group strains, two
monoclonal antibodies (mAbs) were used to select escape mutants of the virus. mAbs 5H4 …
monoclonal antibodies (mAbs) were used to select escape mutants of the virus. mAbs 5H4 …
[HTML][HTML] Unique binding pattern for a lineage of human antibodies with broad reactivity against influenza A virus
Most structurally characterized broadly neutralizing antibodies (bnAbs) against influenza A
viruses (IAVs) target the conserved conformational epitopes of hemagglutinin (HA). Here, we …
viruses (IAVs) target the conserved conformational epitopes of hemagglutinin (HA). Here, we …
[HTML][HTML] Structural basis for the divergent evolution of influenza B virus hemagglutinin
Influenza A and B viruses are responsible for the severe morbidity and mortality worldwide
in annual influenza epidemics. Currently circulating influenza B virus belongs to the …
in annual influenza epidemics. Currently circulating influenza B virus belongs to the …
The influenza B virus hemagglutinin head domain is less tolerant to transposon mutagenesis than that of the influenza A virus
Influenza A and B viruses can continuously evade humoral immune responses by
developing mutations in the globular head of the hemagglutinin (HA) that prevent antibody …
developing mutations in the globular head of the hemagglutinin (HA) that prevent antibody …
Divergent evolutionary trajectories of influenza B viruses underlie their contemporaneous epidemic activity
RK Virk, J Jayakumar, IH Mendenhall… - Proceedings of the …, 2020 - National Acad Sciences
Influenza B viruses have circulated in humans for over 80 y, causing a significant disease
burden. Two antigenically distinct lineages (“B/Victoria/2/87-like” and “B/Yamagata/16/88 …
burden. Two antigenically distinct lineages (“B/Victoria/2/87-like” and “B/Yamagata/16/88 …
Exploration of the emergence of the Victoria lineage of influenza B virus
JM Chen, YJ Guo, KY Wu, JF Guo, M Wang, J Dong… - Archives of …, 2007 - Springer
The Victoria lineage represented by B/Victoria/2/87 is one of the two major distinctive
haemagglutinin (HA) lineages of influenza B virus, and its recent re-emergence has aroused …
haemagglutinin (HA) lineages of influenza B virus, and its recent re-emergence has aroused …
Comparative analysis of evolutionary mechanisms of the hemagglutinin and three internal protein genes of influenza B virus: multiple cocirculating lineages and …
SE Lindstrom, Y Hiromoto, H Nishimura, T Saito… - Journal of …, 1999 - Am Soc Microbiol
Phylogenetic profiles of the genes coding for the hemagglutinin (HA) protein, nucleoprotein
(NP), matrix (M) protein, and nonstructural (NS) proteins of influenza B viruses isolated from …
(NP), matrix (M) protein, and nonstructural (NS) proteins of influenza B viruses isolated from …