Increased Cd2+ biosorption capability of Aspergillus nidulans elicited by crpA deletion

I Boczonádi, Z Török, Á Jakab, G Kónya… - Journal of basic …, 2020 - Wiley Online Library
Abstract The P‐type ATPase CrpA is an important Cu2+/Cd2+ pump in the Aspergilli,
significantly contributing to the heavy metal stress tolerance of these ascomycetous fungi. As …

Functional characterization of genes encoding cadmium pumping P1B-type ATPases in Aspergillus fumigatus and Aspergillus nidulans

I Vig, Z Benkő, BC Gila, Z Palczert, Á Jakab… - Microbiology …, 2023 - Am Soc Microbiol
ABSTRACT Several P1B-type ATPases are important Cd2+/Cu2+ pumps in Aspergillus
species, and they are tightly associated with the heavy metal stress tolerance of these …

Physiological background of the remarkably high Cd2+ tolerance of the Aspergillus fumigatus Af293 strain

V Kurucz, B Kiss, ZM Szigeti, G Nagy… - Journal of basic …, 2018 - Wiley Online Library
The physiological background of the unusually high cadmium tolerance (MIC50> 2 mM) of
Aspergillus fumigatus Af293 was investigated. The cadmium tolerance of the tested …

[HTML][HTML] Copper resistance in Aspergillus nidulans relies on the PI-type ATPase CrpA, regulated by the transcription factor AceA

M Antsotegi-Uskola, A Markina-Iñarrairaegui… - Frontiers in …, 2017 - frontiersin.org
Copper homeostasis has been extensively studied in mammals, bacteria, and yeast, but it
has not been well-documented in filamentous fungi. In this report, we investigated the basis …

[HTML][HTML] AtfA-Independent Adaptation to the Toxic Heavy Metal Cadmium in Aspergillus nidulans

T Emri, B Gila, K Antal, F Fekete, H Moon, JH Yu… - Microorganisms, 2021 - mdpi.com
Cadmium is an exceptionally toxic industrial and environmental pollutant classified as a
human carcinogen. In order to provide insight into how we can keep our environment safe …

Genetic Bypass of Aspergillus nidulans crzA Function in Calcium Homeostasis

RS Almeida, O Loss, AC Colabardini… - G3: Genes …, 2013 - academic.oup.com
After dephosphorylation by the phosphatase calcineurin, the fungal transcription factor CrzA
enters the nucleus and activates the transcription of genes responsible for calcium …

[HTML][HTML] Heavy metal-induced expression of PcaA provides cadmium tolerance to Aspergillus fumigatus and supports its virulence in the Galleria mellonella model

F Bakti, C Sasse, T Heinekamp, I Pócsi… - Frontiers in …, 2018 - frontiersin.org
Most of the metal transporters in Aspergillus fumigatus are yet uncharacterized. Their role in
fungal metabolism and virulence remains unclear. This paper describes the novel PIB-type …

Cadmium uptake and subcellular compartmentation in the ectomycorrhizal fungus Paxillus involutus

D Blaudez, B Botton, M Chalot - Microbiology, 2000 - microbiologyresearch.org
Cadmium uptake and subcellular compartmentation in the ectomycorrhizal fungus Paxillus
involutus were investigated using radiotracer flux analyses. Concentration-dependent Cd2+ …

Mechanism to combat cobalt toxicity in cobalt resistant mutants of Aspergillus nidulans

P Tripathi, S Srivastava - Indian Journal of Microbiology, 2007 - Springer
Characteristics of fungal species tolerant to high levels of metals in natural environment can
be amplified by isolation and selection of resistant mutants. Step-by-step culturing led to …

Two zinc finger transcription factors, CrzA and SltA, are involved in cation homoeostasis and detoxification in Aspergillus nidulans

A Spielvogel, H Findon, HN Arst Jr… - Biochemical …, 2008 - portlandpress.com
To investigate cation adaptation and homoeostasis in Aspergillus nidulans, two transcription-
factor-encoding genes have been characterized. The A. nidulans orthologue crzA of the …