Abstract Background The CYP17A1 gene has been identified to associate with hypertension
in Chinese population. However, the association between CYP17A1 polymorphisms and …

Background: Cytochrome P450 17A1 (CYP17A1) catalyzes the formation and metabolism of
steroid hormones and is required for cortisol and androgens. There is increasing evidence …

Background CYP17A1 gene encodes P450c17 proteins, which is a key enzyme that
catalyzes the formation of sex hormones. Many clinical studies showed that sex hormones …

Background The single-nucleotide polymorphism (SNP) rs11191548, near the CYP17A1
gene, has been identified as being associated with hypertension and systolic blood …

The relationship between CYP17A1 genetic polymorphisms and essential hypertension
(EH) remains unclear. The aim of this study was to investigate the association of CYP17A1 …

Objective: With the development of genome-wide association studies (GWAS) concerning
hypertension, a growing number of susceptibility genes related to hypertension have been …

CYP17A1 gene encodes the cytochrome P450 enzyme CYP17A1, a key enzyme involved in
steroid metabolism. A single nucleotide polymorphism (SNP) near CYP17A1, rs11191548 …

Background: The relationship between CYP17A1 genetic polymorphisms and coronary
artery disease (CAD) remains unclear. The aim of the present study was to assess the …

The CYP17A1 gene, which encodes17α-hydroxylase and 17, 20-lyase, has been identified
as a common hypertension susceptibility locus in a European population. However, the …

Background: Hypertension is one of the leading causes of human death and disability.
CYP24A1 regulates vitamin D activity and is closely linked to hypertension. However, the …