[HTML][HTML] Extracellular nucleotide signaling in solid organ transplantation
S Yeudall, N Leitinger, VE Laubach - American Journal of Transplantation, 2020 - Elsevier
The role of extracellular purine nucleotides, including adenosine triphosphate (ATP) and
adenosine, as modulators of posttransplantation outcome and ischemia-reperfusion injury is …
adenosine, as modulators of posttransplantation outcome and ischemia-reperfusion injury is …
[HTML][HTML] Unlocking the potential of purinergic signaling in transplantation
Purinergic signaling has been recognized as playing an important role in inflammation,
angiogenesis, malignancy, diabetes and neural transmission. Activation of signaling …
angiogenesis, malignancy, diabetes and neural transmission. Activation of signaling …
[HTML][HTML] The role of ectonucleotidases CD39 and CD73 and adenosine signaling in solid organ transplantation
V Roberts, J Stagg, KM Dwyer - Frontiers in Immunology, 2014 - frontiersin.org
Extracellular adenosine is a potent immunomodulatory molecule that accumulates in states
of inflammation. Nucleotides such as adenosine triphosphate and adenosine diphosphate …
of inflammation. Nucleotides such as adenosine triphosphate and adenosine diphosphate …
[HTML][HTML] The role of purinergic signaling in heart transplantation
Y Jiang, J Lin, H Zheng, P Zhu - Frontiers in Immunology, 2022 - frontiersin.org
Heart transplantation remains the optimal treatment option for patients with end-stage heart
disease. Growing evidence demonstrates that purinergic signals mediated by purine …
disease. Growing evidence demonstrates that purinergic signals mediated by purine …
[HTML][HTML] The role of purinergic signaling in the liver and in transplantation: effects of extracellular nucleotides on hepatic graft vascular injury, rejection and metabolism
Extracellular nucleotides (eg ATP, UTP, ADP) are released by activated endothelium,
leukocytes and platelets within the injured vasculature and bind specific cell-surface type-2 …
leukocytes and platelets within the injured vasculature and bind specific cell-surface type-2 …
Purinergic signaling in early inflammatory events of the foreign body response: modulating extracellular ATP as an enabling technology for engineered implants and …
Purinergic signaling is a ubiquitous and vital aspect of mammalian biology in which purines—
mainly adenosine triphosphate (ATP)—are released from cells through loss of membrane …
mainly adenosine triphosphate (ATP)—are released from cells through loss of membrane …
Adenosinergic metabolism pathway: an emerging target for improving outcomes of solid organ transplantation
Extracellular nucleotides are widely recognized as crucial modulators of immune responses
in peripheral tissues. ATP and adenosine are key components of extracellular nucleotides …
in peripheral tissues. ATP and adenosine are key components of extracellular nucleotides …
Administration of exogenous adenosine triphosphate to ischemic skeletal muscle induces an energy-sparing effect: role of adenosine receptors
C Maldonado, SB Pushpakumar… - Journal of Surgical …, 2013 - Elsevier
BACKGROUND: Ischemia–reperfusion injury is a devastating complication that occurs in
allotransplantation and replantation of limbs. Over the years, several preservation strategies …
allotransplantation and replantation of limbs. Over the years, several preservation strategies …
Purinergic regulation of the immune system
Cellular stress or apoptosis triggers the release of ATP, ADP and other nucleotides into the
extracellular space. Extracellular nucleotides function as autocrine and paracrine signalling …
extracellular space. Extracellular nucleotides function as autocrine and paracrine signalling …
[HTML][HTML] The purinergic system in allotransplantation
The purine nucleotide adenosine triphosphate (ATP) is a universal source of energy for any
intracellular reaction. Under specific physiological or pathological conditions, ATP can be …
intracellular reaction. Under specific physiological or pathological conditions, ATP can be …