Vascular endothelial growth factor mediates angiogenic activity during the proliferative phase of wound healing.

NN Nissen, PJ Polverini, AE Koch… - The American journal …, 1998 - ncbi.nlm.nih.gov
Angiogenesis is an essential component of normal wound repair, yet the primary mediators
of wound angiogenesis have not been well described. The current study characterizes the …

[PDF][PDF] Role of angiogenesis and angiogenic factors in acute and chronic wound healing

TM Honnegowda, P Kumar, EGP Udupa… - Plastic and Aesthetic …, 2015 - researchgate.net
Angiogenesis plays a crucial role in wound healing by forming new blood vessels from
preexisting vessels by invading the wound clot and organizing into a microvascular network …

[HTML][HTML] Promotion of lymphangiogenesis by targeted delivery of VEGF-C improves diabetic wound healing

LM Brunner, Y He, N Cousin, J Scholl, LK Albin… - Cells, 2023 - mdpi.com
Chronic wounds represent a major therapeutic challenge. Lymphatic vessel function is
impaired in chronic ulcers but the role of lymphangiogenesis in wound healing has …

Discordant effects of a soluble VEGF receptor on wound healing and angiogenesis

J Jacobi, BYY Tam, U Sundram, G Degenfeld, HM Blau… - Gene therapy, 2004 - nature.com
Soluble receptors to vascular endothelial growth factor (VEGF) can inhibit its angiogenic
effect. Since angiogenesis is involved in wound repair, we hypothesized that adenovirus …

[HTML][HTML] Ischemia Impaired Wound Healing Model in the Rat—Demonstrating Its Ability to Test Proangiogenic Factors

AT Hofmann, P Slezak, S Neumann, J Ferguson… - Biomedicines, 2023 - mdpi.com
Chronic wounds remain a serious clinical problem with insufficient therapeutic approaches.
In this study we investigated the dose dependency of rhVEGF165 in fibrin sealant in both …

Vascularization in skin wound healing: where do we stand and where do we go?

HR Moreira, AP Marques - Current Opinion in Biotechnology, 2022 - Elsevier
Highlights•Neovascularization plays a critical role in wound healing impacting the quality of
neotissue formation.•Biomaterial-based approaches can improve angiogenesis …

Wound healing: future directions.

I Appleton - Idrugs: the Investigational Drugs Journal, 2003 - europepmc.org
Over the years, numerous attempts have been made to accelerate the wound healing
response, with varying degrees of success. This review covers the different phases of repair …

Angiogenesis in wound repair: too much of a good thing?

C Han, M Barakat, LA DiPietro - Cold Spring Harbor …, 2022 - cshperspectives.cshlp.org
Angiogenesis, or the growth of new blood vessels from the preexisting vasculature, is a
visible and important component of wound repair. When tissue damage occurs, disruption of …

The role of vascular endothelial growth inhibitor in wound healing

KP Conway, P Price, KG Harding… - International Wound …, 2007 - Wiley Online Library
Vascular endothelial growth inhibitor (VEGI) is an endothelial cell‐specific cytokine and a
potent inhibitor of endothelial cell proliferation and angiogenesis. The role of VEGI in …

Angiogenesis in wound repair: angiogenic growth factors and the extracellular matrix

J Li, YP Zhang, RS Kirsner - Microscopy research and …, 2003 - Wiley Online Library
Angiogenesis is critical to wound repair. Newly formed blood vessels participate in
provisional granulation tissue formation and provide nutrition and oxygen to growing tissues …