Role of the microbiome in allergic disease development

AC Aguilera, IA Dagher, KM Kloepfer - Current allergy and asthma reports, 2020 - Springer
Abstract Purpose of Review Evidence suggests that the microbiome of the skin,
gastrointestinal tract, and airway contribute to health and disease. As we learn more about …

Allergy associations with the adult fecal microbiota: analysis of the American Gut Project

X Hua, JJ Goedert, A Pu, G Yu, J Shi - EBioMedicine, 2016 - thelancet.com
Background Alteration of the gut microbial population (dysbiosis) may increase the risk for
allergies and other conditions. This study sought to clarify the relationship of dysbiosis with …

A calm, dispassionate look at skin microbiota in atopic dermatitis: an integrative literature review

P Wan, J Chen - Dermatology and therapy, 2020 - Springer
Atopic dermatitis (AD) is a chronic common inflammatory skin disorder with clinical
characteristics of pruritic, dry, and recurrent flares that involve the whole body. Recent …

Turning the inside out: the microbiology of atopic dermatitis

H Brüssow - Environmental microbiology, 2016 - Wiley Online Library
Allergy is on the rise worldwide. The hygiene hypothesis of atopic diseases linked microbes
with atopic dermatitis (AD) both as drivers and modulators of skin pathology. The earlier …

Microbiome composition and its impact on the development of allergic diseases

DG Peroni, G Nuzzi, I Trambusti, ME Di Cicco… - Frontiers in …, 2020 - frontiersin.org
Allergic diseases, such as food allergy (FA), atopic dermatitis (AD), and asthma, are
heterogeneous inflammatory immune-mediated disorders that currently constitute a public …

Implication of human bacterial gut microbiota on immune-mediated and autoimmune dermatological diseases and their comorbidities: a narrative review

R Colucci, S Moretti - Dermatology and therapy, 2021 - Springer
During the last decade, the advent of modern sequencing methods (next generation
techniques, NGS) has helped describe the composition of the human gut microbiome …

The causal relationship between gut microbiota and type 2 diabetes: a two-sample Mendelian randomized study

K Sun, Y Gao, H Wu, X Huang - Frontiers in Public Health, 2023 - frontiersin.org
Background Type 2 diabetes mellitus (T2DM) is a commonly observed metabolic anomaly
globally, and as of the present time, there's no recognized solution. There is an increasing …

[PDF][PDF] Microbiome and allergy: new insights and perspectives

E Zubeldia Varela, TC Barker Tejeda… - … allergology & clinical …, 2022 - jiaci.org
The role of the microbiome in the molecular mechanisms underlying allergy has become
highly relevant in recent years. Studies are increasingly suggesting that altered composition …

Gut microbiota and type 1 diabetes: a two-sample bidirectional Mendelian randomization study

M Luo, M Sun, T Wang, S Zhang, X Song… - Frontiers in Cellular …, 2023 - frontiersin.org
Objective The real causal relationship between human gut microbiota and T1D remains
unclear and difficult to establish. Herein, we adopted a two-sample bidirectional mendelian …

The microbiome as a gateway to prevention of allergic disease development

KM Kloepfer, KE McCauley, PV Kirjavainen - The Journal of Allergy and …, 2022 - Elsevier
Allergic diseases exclusively affect tissues that face environmental challenges and harbor
endogenous bacterial microbiota. The microbes inhabiting the affected tissues may not be …