Will complement inhibition be the new target in treating COVID-19–related systemic thrombosis?
CM Campbell, R Kahwash - Circulation, 2020 - Am Heart Assoc
June 2, 2020 Circulation. 2020; 141: 1739–1741. DOI: 10.1161/CIRCULATIONAHA.
120.047419 1740 nonsurvivors. Given this diffuse thrombosis, Chinese physicians …
120.047419 1740 nonsurvivors. Given this diffuse thrombosis, Chinese physicians …
[HTML][HTML] Is COVID-19 associated thrombosis caused by overactivation of the complement cascade? A literature review
A Fletcher-Sandersjöö, BM Bellander - Thrombosis research, 2020 - Elsevier
Severe acute respiratory syndrome coronavirus 2 is responsible for the current COVID-19
pandemic resulting in an escalating number of cases and fatalities worldwide. Preliminary …
pandemic resulting in an escalating number of cases and fatalities worldwide. Preliminary …
Severe COVID‐19 infection and thrombotic microangiopathy: success does not come easily.
E Gavriilaki, RA Brodsky - British journal of haematology, 2020 - search.ebscohost.com
Severe COVID-19 infection and thrombotic microangiopathy: success does not come easily
Keywords: complement; complement inhibition; COVID-19; thrombotic microangiopathy EN …
Keywords: complement; complement inhibition; COVID-19; thrombotic microangiopathy EN …
[HTML][HTML] Is the COVID‐19 thrombotic catastrophe complement‐connected?
EM Conway, ELG Pryzdial - Journal of Thrombosis and Haemostasis, 2020 - Elsevier
In December 2019, the world was introduced to a new betacoronavirus, referred to as
severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) for its propensity to cause …
severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) for its propensity to cause …
[HTML][HTML] COVID‐19: a collision of complement, coagulation and inflammatory pathways
AJ Chauhan, LJ Wiffen, TP Brown - Journal of Thrombosis and …, 2020 - Elsevier
COVID‐19 is frequently accompanied by a hypercoagulable inflammatory state with
microangiopathic pulmonary changes that can precede the diffuse alveolar damage …
microangiopathic pulmonary changes that can precede the diffuse alveolar damage …
Complement associated microvascular injury and thrombosis in the pathogenesis of severe COVID-19 infection: a report of five cases
Acute respiratory failure and a systemic coagulopathy are critical aspects of the morbidity
and mortality characterizing infection with severe acute respiratory distress syndrome …
and mortality characterizing infection with severe acute respiratory distress syndrome …
The state of complement in COVID-19
Hyperactivation of the complement and coagulation systems is recognized as part of the
clinical syndrome of COVID-19. Here we review systemic complement activation and local …
clinical syndrome of COVID-19. Here we review systemic complement activation and local …
Direct activation of the alternative complement pathway by SARS-CoV-2 spike proteins is blocked by factor D inhibition
J Yu, X Yuan, H Chen, S Chaturvedi… - Blood, The Journal …, 2020 - ashpublications.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly contagious
respiratory virus that can lead to venous/arterial thrombosis, stroke, renal failure, myocardial …
respiratory virus that can lead to venous/arterial thrombosis, stroke, renal failure, myocardial …
Complement and coagulation: key triggers of COVID-19–induced multiorgan pathology
B Ghebrehiwet, EI Peerschke - The Journal of clinical …, 2020 - Am Soc Clin Investig
In a stunningly short period of time, the unexpected coronavirus disease 2019 (COVID-19)
pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS–CoV-2), has …
pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS–CoV-2), has …
COVID-19: complement, coagulation, and collateral damage
MW Lo, C Kemper, TM Woodruff - The Journal of Immunology, 2020 - journals.aai.org
Abstract Coronavirus disease of 2019 (COVID-19) is a highly contagious respiratory
infection that is caused by the severe acute respiratory syndrome coronavirus 2. Although …
infection that is caused by the severe acute respiratory syndrome coronavirus 2. Although …