Post-transcriptional regulation of gene expression, including mRNA localization, translation
and decay, is ubiquitous yet still largely unexplored. How is the post-transcriptional …

RNA-binding proteins (RBPs) have roles in the regulation of many post-transcriptional steps
in gene expression, but relatively few RBPs have been systematically studied. We searched …

The vast landscape of RNA-protein interactions at the heart of post-transcriptional regulation
remains largely unexplored. Indeed it is likely that, even in yeast, a substantial fraction of the …

Hundreds of RNA-binding proteins (RBPs) control diverse aspects of post-transcriptional
gene regulation. To identify novel and unconventional RBPs, we probed high-density …

Post-transcriptional gene regulation is mediated through complex networks of protein–RNA
interactions. The targets of only a few RNA binding proteins (RBPs) are known, even in the …

Background Protein-RNA interactions are integral components of nearly every aspect of
biology, including regulation of gene expression, assembly of cellular architectures, and …

Cytoplasmic mRNA localization is a mechanism used by many organisms to generate
asymmetry and sequester protein activity. In the yeast Saccharomyces cerevisiae, mRNA …

In eukaryotic organisms, gene expression requires an additional level of coordination that
links transcriptional and posttranslational processes. Messenger RNAs have traditionally …

Gene expression is regulated at each step from chromatin remodeling through translation
and degradation. Several known RNA‐binding regulatory proteins interact with specific RNA …

The regulation of translation provides a rapid and direct mechanism to modulate the cellular
proteome. In eukaryotes, an established model for the recruitment of ribosomes to mRNA …