RNA-binding proteins are key players in the regulation of gene expression. In this Progress
article, we discuss state-of-the-art technologies that can be used to study individual RNA …

Although in vitro methods have been used to identify putative targets of mRNA-binding
proteins, direct in vivo methods are needed to identify endogenously associated mRNAs …

mRNA localization is an important posttranscriptional method of targeting proteins to their
site of function. The sorting of transcripts to their correct intracellular destination is achieved …

Regulation of gene expression is executed in many cases by RNA-binding proteins (RBPs)
that bind to mRNAs as well as to non-coding RNAs. RBPs recognize their RNA target via …

Given their central role in translation, splicing, localization and stability of transcripts, RNA
binding proteins (RBPs) are key regulators of several cellular processes. While experimental …

Some of the classical paradigms of gene regulation have been challenged by global‐scale
analysis of eukaryotic transcriptional and post‐transcriptional gene regulation (PTGR), made …

After an RNA is transcribed, it undergoes a variety of processing steps that can change the
encoded protein sequence (through alternative splicing and RNA editing), regulate the …

Messenger RNAs interact with a number of different molecules that determine the fate of
each transcript and contribute to the overall pattern of gene expression. These interactions …

It is now established that base-pairing regulatory RNAs are key players in post-
transcriptional regulatory networks where they affect the translation and/or stability of their …

The crucial role of the non-coding portion of genomes is now widely acknowledged. In
particular, mRNA untranslated regions are involved in many post-transcriptional regulatory …